新西兰兔下颌骨牵引成骨早期拆除牵引装置植入钛钉对新骨形成的影响  

Effects of early removal of the distractor and implantation of titanium nail on the formation of new bones in the mandible of New Zealand rabbits

作　　者：吴章 李泽毓 赵贵然 翟江云 姚玉胜 Wu Zhang;Li Zeyu;Zhao Guiran;Zhai Jiangyun;Yao Yusheng(Department of Stomatology,Third Affiliated Hospital,Jinzhou Medical University,Jinzhou 121001,China;Department of Stomatology,First Affiliated Hospital,Jinzhou Medical University,Jinzhou 121001,China)

机构地区：[1]锦州医科大学附属第三医院口腔科,锦州121001 [2]锦州医科大学附属第一医院口腔科,锦州121001

出　　处：《解剖学杂志》2020年第1期43-46,共4页Chinese Journal of Anatomy

摘　　要：目的:利用锥形束CT(CBCT)研究新西兰兔下颌骨矩形截骨后,早期拆除牵引装置植入钛钉对新骨形成的影响,探讨牵引成骨早期拆除牵引装置的可能性。方法:新西兰兔下颌骨矩形截骨12 mm×4 mm,植入自制牵引装置。牵引5 d后,随机分为稳定4周、稳定8周、钛钉植入3组。前2组分别于稳定期4周、8周时处死动物;钛钉植入组,稳定期4周时,取出牵引器植入钛钉,4周后处死动物;拍摄CBCT和X线片。结果:兔下颌骨垂直高度平均增加(2.25±0.41)mm。稳定4周、8周和钛钉植入组的术区CT值分别为(80.00±12.36)Hu、(293.00±37.66)Hu和(289.25±38.87)Hu。稳定4周术区CT值低于稳定8周和钛钉植入组,后2组CT值相近。结论:早期拆除牵引装置植入钛钉与常规固定相比,骨形成没有明显影响,临床应用可有效地缩短牵引成骨的时间。Objective:To study the effect of early distractor removal and implantation of titanium nail on new bone formation after rectangular osteotomy of the mandible of New Zealand rabbits by cone beam CT(CBCT),and to investigate the possibility of early removal of the distractor after distraction osteogenesis.Methods:New Zealand rabbits were subject to rectangular osteotomy of 12 mm×4 mm in their mandibles and implanted with a homemade distractor.After 5 days of traction,the experimental rabbits were randomly divided into stable 4-week group,stable 8-week group,and titanium nail implantation group.The first two groups were sacrificed at 4 and 8 weeks,respectively.For the titanium nail implantation group,the distractor was removed and implanted with titanium nails at 4 weeks of stabilization;animals were sacrificed after 4 weeks,and CBCT and X-rays were taken.Results:The vertical height of the mandible of the experimental rabbits increased by(2.25±0.41)mm.The average CT values of the operation area in the 4-week group,the 8-week group,and the titanium nail implantation group were(80.00±12.36)Hu,(293.00±37.66)Hu,and 289.25 Hu±38.87 Hu.The average CT value of the operation area in the stable 4-week group was lower than that of the stable 8-week group and the titanium nail implantation group,and the average CT values of the latter two groups were similar.Conclusion:Compared with the conventional fixation,the method of removing the distractor and implanting the titanium nail in the early stage has no significant effect on the formation of new bones.The clinical application of this method can effectively shorten the time of distraction osteogenesis.

关 键 词：牵引成骨 下颌骨 兔 骨密度 

分 类 号：R783.5[医药卫生—口腔医学]