新辅助化疗后乳腺癌保乳手术中射频消融治疗的临床观察  

Clinical observation of radiofrequency ablation in breast-conserving surgery after neoadjuvant chemotherapy

作　　者：张大庆 张慧明[1] 葛智成[1] 王子函[1] 高银光[1] 高国璇 王慧[1] 苑著[1] 张忠涛[1] 屈翔[1] Zhang Daqing;Zhang Huiming;Ge Zhicheng;Wang Zihan;Gao Yinguang;Gao Guoxuan;Wang Hui;Yuan Zhu;Zhang Zhongtao;Qu Xiang(Department of General Surgery,Beijing Friendship Hospital,Capital Medical University,National Clinical Research Center for Digestive Diseases,Beijing 100050,China)

机构地区：[1]首都医科大学附属北京友谊医院普通外科国家消化系统疾病临床医学研究中心,100050

出　　处：《国际外科学杂志》2020年第1期31-35,共5页International Journal of Surgery

摘　　要：目的评估射频消融术在新辅助化疗后乳腺癌保乳手术中的治疗效果。方法回顾性分析2015年4月—2018年9月首都医科大学附属北京友谊医院收治的30例乳腺癌患者的病例资料,平均年龄54.3岁,范围为28~70岁,患者均经病理学检查确诊为乳腺浸润性导管癌,患者均于新辅助化疗后行保乳手术,之后接受射频消融治疗。观察患者的临床病理特征、术后并发症、复发转移及美容效果。结果30例乳腺癌保乳手术患者均成功完成射频消融治疗。平均门诊随访22.5个月,范围为2~43个月,无局部复发或转移;2例(6.67%)出现皮肤烧伤,6例(20.00%)原位形成实性结节;美容效果满意率为86.67%(26/30)。结论射频消融术应用于保乳手术具有较高的成功率,并发症发生率相对较低,并且射频消融术可改善保乳手术的术后美容效果,提高局部控制率。Objective To evaluate the efficacy of radiofrequency ablation in breast-conserving surgery followed neoadjuvant chemotherapy.Methods Retrospective analysis of 30 cases of breast cancer patients admitted to Beijing Friendship Hospital,Capital Medical University from April 2015 to September 2018.The average age was 54.3 years and the range was 28 to 70 years.For breast invasive ductal cancer,patients underwent breast-conserving surgery after neoadjuvant chemotherapy,and then received radiofrequency ablation.The clinical and pathological characteristics,postoperative complications,recurrence and metastasis,and cosmetic effects were observed.Results All 30 patients with breast-conserving surgery successfully completed radiofrequency ablation.The average outpatient follow-up was 22.5 months,ranging from 2 to 43 months,without local recurrence or metastasis;skin burns occurred in 2 cases(6.67%),and solid nodules formed in situ in 6 cases(20.00%);cosmetic satisfaction rate was 86.67%(26/30).Conclusions The radiofrequency ablation techniques applied in breast-conserving surgery have a high rate of technical success with relative low complication rates.And the radiofrequency ablation techniques may improve the cosmetic results after breast-conserving surgery and enhance local control.

关 键 词：乳腺肿瘤 射频消融 新辅助化疗 保乳手术 局部控制 治疗结果 

分 类 号：R737[医药卫生—肿瘤]