血清学指标联合检测在急性脑梗死诊断及预后评估中的应用  

Combined detection of serological indicators in the diagnosis of acute cerebral infarction and prognostic assessment

作　　者：赵丽娜 Zhao Lina(Liaoning Huludao Second People's Hospital,Huludao,Liaoning,125004,China)

机构地区：[1]辽宁省葫芦岛市第二人民医院

出　　处：《当代医学》2020年第7期80-82,共3页Contemporary Medicine

摘　　要：目的观察Hcy、hs-CRP、MPV联合检测在急性脑梗死诊断及预后评估中的应用价值。方法选取本院2016年11月至2017年10月收治确诊的急性脑梗死患者76例为观察组,根据NIHSS量表评估患者预后,<21分为预后良好组(n=52),≥22分则为预后不良组(n=24),另选取同期于本院进行健康体检的76名健康者为对照组。对比两组Hcy、hs-CRP、MPV水平,并分析Hcy、hs-CRP、MPV及三者联合检测在急性脑梗死中的诊断准确率及预后评估的相关性。结果观察组Hcy、hs-CRP、MPV均高于对照组,差异有统计学意义(P<0.05);Hcy+hs-CRP+MPV对急性脑梗死的检出率均高于各项指标单一检测,差异有统计学意义(P<0.05);预后良好组Hcy、hs-CRP、MPV均低于预后不良组,差异有统计学意义(P<0.05);Hcy、hs-CRP、MPV与急性脑梗死患者预后均呈正相关(r=0.309、0.440、0.598,P<0.05)。结论Hcy、hs-CRP、MPV联合检测急性脑梗死具有较高的检出率,且各项水平与急性脑梗死患者预后呈正相关,因此Hcy、hs-CRP、MPV联合可为临床急性脑梗死患者早期诊断及预后的评估提供依据。Objective To observe the value of Hcy,hs-CRP,MPV combined detection in the diagnosis and prognosis evaluation of acute cerebral infarction.Methods 76 patients with acute cerebral infarction diagnosed in our hospital from November 2016 to October 2017 were selected as the observation group.The prognosis of the patients was evaluated according to NIHSS scale.<21 points was divided into good prognosis group(n=52),≥21 scores was poor prognosis group(n=24)and 76 healthy persons who underwent physical examination in our hospital at the same time as the control group.The levels of Hcy,hs-crp and MPV in the two groups were compared,and the correlation between the diagnostic accuracy and progno sis of Hcy,hs-crp,MPV and the three combined tests in acute cerebral infarction was analyzed.Results The detection rate of Hcy,hs-CRP,MPV in the observation group was significantly higher than that in the control group(P<0.05),the detection rate of acute cerebral infarction in the observa tion group was significantly higher than that in the control group(P<0.05),the Hcy,hs-CRP,MPV in the good prognosis group was lower than that in the poor prognosis group(P<0.05),and the Hcy,hs-CRP,MPV and acute cerebral infarction were significantly lower than those in the poor prog nosis group(P<0.05).The prognosis of dead patients was positively correlated with the prognosis of patients with acute cerebral infarction(r=0.309,0.440,0.598,P<0.05).Conclusion The combined detection rate of Hcy,hs-CRP,MPV in patients with acute cerebral infarction is high,and the lev els are positively correlated with the prognosis of patients with acute cerebral infarction.Therefore,the combination of Hcy,hs-CRP,MPV can pro vide the basis for the early diagnosis and prognosis evaluation of patients with acute cerebral infarction.

关 键 词：急性脑梗死 HCY HS-CRP MPV 预后评估 

分 类 号：R743.33[医药卫生—神经病学与精神病学] R446.1[医药卫生—临床医学]