盐酸达克罗宁胶浆在结肠镜检查中的应用效果  

Application effect of Dacronin Hydrochloride Mucilage in colonoscopy

作　　者：胡俊 范艳君 李志晋 黄晓美 HU Jun;FAN Yan-jun;LI Zhi-jin;HUANG Xiao-mei(Department of Digestion,the 908th Hospital of PLA Joint Logistic Support Force,Jiangxi Province,Yingtan 335000,China)

机构地区：[1]解放军联勤保障部队第九〇八医院消化科

出　　处：《中国当代医药》2020年第3期94-97,共4页China Modern Medicine

摘　　要：目的观察口服不同剂量的盐酸达克罗宁胶浆在结肠镜检查中的应用效果。方法选择2018年7月1日~12月31日我院消化科行结肠镜检查的843例患者作为研究对象,按照口服盐酸达克罗宁胶浆剂量的不同将其随机分为高剂量组(288例)、低剂量组(281例)及对照组(274例)。各组患者术前均予聚乙二醇行肠道准备。在肠镜检查术前1 h,高剂量组给予盐酸达克罗宁胶浆40 ml配100 ml温水,低剂量组给予盐酸达克较宁胶浆20 ml配100 ml温水口服,对照组不予服用盐酸达克罗宁胶浆,未采取任何措施。三组均由同一位资深内镜操作医师进行肠镜检查,评价患者的肠道泡沫量分级情况、肠道清洁度评分;记录并比较三组的结肠镜进镜及检查操作时间、息肉检出率。结果高剂量组和低剂量组的泡沫量分级情况优于对照组,差异有统计学意义(P<0.05)。高剂量组的肠道泡沫量分级情况优于低剂量组,差异有统计学意义(P<0.05)。高剂量组、低剂量组及对照组的Boston肠道准备量表(BBPS)评分分别为(7.84±0.97)、(7.96±1.04)和(7.88±1.09)分。三组的BBPS评分比较,差异无统计学意义(P>0.05)。三组的结肠镜进镜时间比较,差异无统计学意义(P>0.05)。高剂量组及低剂量组的结肠镜检查时间短于对照组,差异有统计学意义(P<0.05)。高剂量组的结肠镜检查时间短于低剂量组,差异有统计学意义(P<0.05)。高剂量组、低剂量组的总息肉与微小息肉检出率高于对照组,差异有统计学意义(P<0.05)。高剂量组的总息肉与微小息肉检出率与低剂量组比较,差异无统计学意义(P>0.05)。高剂量组和低剂量组均未出现头晕、头痛、胸闷、心悸及药物过敏等严重不良反应。所有患者中有11例患者在肠道准备过程中出现恶心、呕吐、腹胀等不适,其中高剂量组3例,低剂量组5例,对照组3例,考虑与短时间内进食大量水进肠道准备有关,与口服盐酸达�Objective To observe the application effect of oral different doses of Dacronin Hydrochloride Mucilage in colonoscopy.Methods From July 1 to December 31,2018,843 patients who underwent colonoscopy in the digestive department of our hospital were randomly divided into high dose group(288 cases),low dose group(281 cases)and control group(274 cases).All the patients in each group were prepared with Polyethylene Glycol before operation.A total of 40 ml and 100 ml warm water were given to the high dose group 1 hour before enteroscopy,and 20 ml and 100 ml warm water were given to the low dose group.The control group did not take Dacronin Hydrochloride Mucilage,did not take any measures.The colonoscopy was performed by the same senior endoscopic surgeon to evaluate the grade of intestinal foam and the score of intestinal cleanliness,and the colonoscopy time,operation time and polyp detection rate of the three groups were recorded and compared.Results The foam quantity grade of the high dose group and the low dose group were better than that of the control group,and the differences were statistically significant(P<0.05).The grade of intestinal foam volume in the high-dose group was better than that in the low-dose group,and the difference was statistically significant(P<0.05).The Boston bowel preparation scale(BBPS)scores of the high dose group,the low dose group and the control group were(7.84±0.97),(7.96±1.04)and(7.88±1.09)points,respectively.There were no significant differences in BBPS scores among the three groups(P>0.05).There was no significant difference in colonoscopy time in the three groups(P>0.05).The colonoscopy time of the high dose group and the low dose group was shorter than that of the control group,and the differences were statistically significant(P<0.05).The colonoscopy time of the high dose group was shorter than that of the low dose group,and the difference was statistically significant(P<0.05).The detection rate of total polyps and micropolyps in the high dose group was not significantly differ

关 键 词：结肠镜检查 盐酸达克罗宁胶浆 祛泡 肠道清洁度 息肉 

分 类 号：R574.62[医药卫生—消化系统]