5-苯甲酰基-2,4-二羟基苯甲醛的合成、晶体结构及紫外吸收性能研究  

Synthesis,crystal structure and ultraviolet absorption characteristics of 5-benzoyl-2,4-dihydroxybenzaldehyde

作　　者：杨春来 陈俐 彭秀丽 王治国 YANG Chun-lai;CHEN Li;PENG Xiu-li;WANG Zhi-guo(Hubei Key Laboratory of Mine Environmental Pollution Control&Remediation,School of Chemical and Materials Engineering,Hubei Polytechnic University,Huangshi 435003,China)

机构地区：[1]湖北理工学院化学与化工学院矿区环境污染控制与修复湖北省重点实验室

出　　处：《化学研究与应用》2020年第2期303-307,共5页Chemical Research and Application

基　　金：湖北理工学院校级科研项目(17xjz05A)

摘　　要：以2,4-二羟基二苯甲酮为原料,经过醚化、Vilsmeier-Haack反应和脱甲基化三步反应制备5-苯甲酰基-2,4-二羟基苯甲醛,反应总收率达到74.1%。通过1H NMR、13C NMR、IR、MS和X-ray单晶衍射对目标产物进行结构表征,晶体结构显示两个苯环并不共平面,分子内和分子间的氢键连接分子形成三维网状结构。考查该化合物的紫外吸收性能,在293 nm和324 nm有很好的紫外吸收,兼具长波紫外线UVA和中波紫外线UVB的吸收性能。5-benzoyl-2,4-dihydroxybenzaldehyde was prepared from 2,4-dihydroxybenzophenone by etherification,Vilsmeier-Haack reaction and demethylation.The overall yield reached 74.1%.The structure of the target compound was characterized by 1H NMR,13C NMR,IR,MS,and X-ray single crystal diffraction.The crystal structure showed that the two benzene rings were not coplanar.and intramolecular hydrogen bonds and intermolecular hydrogen bonds connect molecules into a three-dimensional network structure.The UV absorption properties of the compound were investigated.The compound has good ultraviolet absorption at 293 and 324 nm,and has both long-wave ultraviolet UVA and medium-wave ultraviolet UVB absorption properties.

关 键 词：5-苯甲酰基-2 4-二羟基苯甲醛 合成 晶体结构 紫外吸收 

分 类 号：R914.5[医药卫生—药物化学]