p16,E6/E7蛋白与宫颈癌及癌前病变相关性的研究进展  

Research progress in correlation between p16, E6/E7 proteins and cervical cancer and precancerous lesions

作　　者：曹洁琼 王晓宇(综述) 赵烨(审校)[2] CAO Jieqiong;WANG Xiaoyu;ZHAO Ye(First Clinical Medical College,First Hospital,Shanxi Medical University,Taiyuan 030000,China;Department of Gynecology,First Hospital,Shanxi Medical University,Taiyuan 030000,China)

机构地区：[1]山西医科大学第一临床医学院,太原030000 [2]山西医科大学第一医院妇科,太原030000

出　　处：《临床与病理杂志》2020年第2期443-447,共5页Journal of Clinical and Pathological Research

摘　　要：宫颈癌是女性最常见的、发病率较高、但完全可以通过筛查早期发现并进行有效防治的恶性肿瘤。在宫颈病变中,高危型HPV病毒的持续感染是导致其发生发展的明确病因,近年来,p16,HPV E6/E7蛋白在明确宫颈病变的发病机制、诊断、临床分流等方面的作用备受关注。Cervical cancer is the most common malignant tumor in women with high incidence,but can be detected early and effectively prevented by screening.In cervical lesions,the persistent infection of high-risk HPV virus is a clear cause of its development.In recent years,the role of P16 and HPV E6/E7 proteins in the pathogenesis,diagnosis and clinical shunt of cervical lesions has attracted much attention.

关 键 词：宫颈病变 P16 HPV E6/E7 免疫组织化学分析 

分 类 号：R737.33[医药卫生—肿瘤]