多途径介入手术与单纯抗凝治疗颅内静脉系统血栓  

Cerebral venous sinus thrombosis:Endovascular treatment with different aproaches and anticoagulant therapy

作　　者：苏旭东[1] 姚冬静 于江华[1] 刘增品[1] 周存河[1] 刘桂元 SU Xudong;YAO Dongjing;YU Jianghua;LIU Zengpin;ZHOU Cunhe;LIU Guiyuan(Department of Neurology,the Second Hospital of Hebei Medical University,Hebei Key Laboratory of Neurology,Shijiazhuang 050000,China;Department of Pediatrics,Hebei General Hospital,Shijiazhuang 050051,China;Department of Internal Medicine,Fucheng County People's Hospital,Fucheng 053799,China)

机构地区：[1]河北医科大学第二医院神经内科河北省神经病学重点实验室,河北石家庄050000 [2]河北省人民医院儿科,河北石家庄050051 [3]阜城县人民医院内科,河北阜城053799

出　　处：《中国介入影像与治疗学》2020年第2期75-79,共5页Chinese Journal of Interventional Imaging and Therapy

基　　金：河北医科大学第二医院科学研究基金项目(2h201824)

摘　　要：目的对比多途径介入手术与单纯抗凝治疗颅内静脉系统血栓(CVST)的疗效。方法回顾性分析88例CVST患者,其中47例接受多途径介入手术治疗(手术治疗组)、41例接受单纯抗凝治疗(对照组);术后随访6个月,比较2组疗效。结果手术治疗组出院时、3个月和6个月随访时改良Rankin量表(mRS)评分和美国立卫生研究院卒中量表(NIHSS)评分分别为1(1,2)、1.43±0.50,1(0,2)、1.04±0.33,1(0,1)、0.87±0.28,均低于对照组[2(1,2)、2.20±0.62,2(1,2)、1.59±0.49,1(0,2)、1.37±0.37,P均<0.05]。结论多途径介入手术治疗CVST疗效优于单纯抗凝,可降低致残率,改善患者生活质量。Objective To compare the efficacy of multi-channel endovascular treatments and anticoagulant therapy in treatment of cerebral venous sinus thrombosis(CVST).Methods Data of 88 CVST patients were analyzed retrospectively,including 47 patients treated with multi-channel endovascular treatments(experimental group)and 41 patients treated with anticoagulation therapy(control group).Clinical follow-up was carried out for 6 months,and the efficacies were compared between the two groups.Results At the discharge,3-month and 6-month follow-up points,modified Rankin scale(mRS)score and National Institute of Health stroke scale(NIHSS)score of the experimental group were 1(1,2)and 1.43±0.50,1(0,2)and 1.04±0.33,1(0,1)and 0.87±0.28,lower than that of control group(2[1,2]and 2.20±0.62,2[1,2]and 1.59±0.49,1[0,2]and 1.37±0.37,all P<0.05).Conclusion Compared with traditional anticoagulant therapy,multi-channel endovascular treatments have better efficacies,which can reduce the disability rate and improve the quality of life of CVST patients.

关 键 词：静脉窦血栓形成 颅内 血管内治疗 抗凝治疗 

分 类 号：R743[医药卫生—神经病学与精神病学] R815[医药卫生—临床医学]