某三甲医院输血不良反应识别及处理情况分析  

Recognition and treatment of adverse transfusion reactions in a grade A class three hospital

作　　者：魏玉平[1] 徐畅 王浩[1] 陈吉翠 高海燕[1] 马现君[1] WEI Yuping;XU Chang;WANG Hao;CHEN Jicui;GAO Haiyan;MA Xianjun(Department of Blood Transfusion,Qilu Hospital,Shandong University,Jinan,250012,China)

机构地区：[1]山东大学齐鲁医院输血科

出　　处：《临床血液学杂志（输血与检验）》2019年第6期952-955,共4页Journal of Clinical Hematology(Blood Transfusion & Laboratory Medicine)

摘　　要：目的:分析山东大学齐鲁医院输血不良反应发生情况,评估医护人员对输血不良反应识别能力及处理水平。方法:统计2012-01-2018-12上报输血不良反应,查阅病历和相关实验记录,最终纳入123例进行分析,并从不良反应的症状识别、反应与输血相关性及反应的严重程度3个方面进行评估。结果:123例输血不良反应中男65例(52.8%),女58例(47.2%);包含不同反应症状147例,其中有发热症状42例(28.6%),过敏症状72例(49.0%),呼吸道症状20例(13.6%),其他症状13例(8.8%);147例不良反应症状中,129例(87.8%)症状与输血肯定相关、12例(8.2%)可能与输血相关,6例(4.1%)可能与输血不相关;123例不良反应中60例(48.8%)为轻度反应,58例(47.1%)为中重度反应,5例(4.1%)为致命性反应。结论:我院输血不良反应主要为急性输血反应;大部分科室医护人员对输血不良反应的识别较准确,部分上报不良反应可能与输血不相关;输血不良反应用药还尚需进一步规范化;医护人员对输血反应识别较准确、处理及时,无输血不良反应相关死亡。Objective:To summarize and analyze the occurrence of adverse reactions of blood transfusion in our hospital in the past seven years,and to evaluate the level of recognition and treatment of adverse reactions of blood transfusion by medical staff in our hospital. Method:From January 2012 to December 2018,123 cases of adverse transfusion reactions(ATRs)were were analyzed according to blood components,clinical symptoms and clinical treatment.The symptoms of ATRs were identified,and the correlation was analyzed.The severity of the response was assessed in three aspects. Result:123 cases of adverse transfusion included 65 males(52.8%)and 58 females(47.2%).Among them,42 cases(28.6%)reported fever,72 cases(49.0%)allergic symptoms,20 cases(13.6%)respiratory symptoms and 13 cases(8.8%)other symptoms.129(87.8%)adverse reactions were positively correlated with blood transfusion,12(8.2%)might be correlated with blood transfusion,and 6(4.1%)symptoms might not be correlated with blood transfusion.Of all the adverse reactions,60(48.8%)were mild,58(47.1%)moderate to severe and 5(4.1%)fatal.Conclusion:The main adverse reactions of blood transfusion in our hospital were acute non-hemolytic transfusion reaction,and the identification of delayed transfusion reaction was deficient.Most departments recognize the adverse reactions of blood transfusion more accurately,and some reported adverse reactions may not be related to blood transfusion.Drug use of ATRs in blood transfusion should be further standardized.Clinical management of adverse reactions was timely,and no transfusion-related deaths occurred.

关 键 词：输血不良反应 发热 过敏 

分 类 号：R574[医药卫生—消化系统]