济南市哨点医院食源性致泻大肠埃希氏菌感染病例流行特征分析  

Epidemiological characteristics of foodborne diarrheagenic Escherichia coli infection in sentinel hospital of Jinan City

作　　者：杨丽[1] 刘铁诚[1] 李健[1] 孙延斌[1] 张军[1] 李士凯[1] YANG Li;LIU Tie-cheng;LI Jian;SUN Yan-bin;ZHANG Jun;LI Shi-kai(Jinan Center for Disease Control and Prevention,Jinan,Shandong 250021,China)

机构地区：[1]济南市疾病预防控制中心

出　　处：《现代预防医学》2020年第4期595-598,共4页Modern Preventive Medicine

摘　　要：目的了解济南市食源性散发腹泻病例中致泻大肠埃希氏菌(diarrheagenic Escherichia coli,DEC)感染的流行状况。方法采集2014-2018年济南市两家食源性疾病主动监测哨点医院的腹泻病例粪便标本,并收集病例的临床和流行病学资料进行分析。率或构成比的比较用χ2或Fisher确切概率值检验,检验水准α=0.05。结果2014-2018年共采集食源性散发腹泻病例粪便标本2291份,DEC阳性检出率为28.55%(654/2291),其中EAEC阳性病例占60.39%。654例DEC阳性病例中,男女性别比为1.30:1,差异无统计学意义(χ2=0.118,P=0.731)。≥60组阳性检出率最高,为34.97%(248/624)(χ2=30.48,P<0.001)。DEC以第二季度的阳性率最高,且各季度间差异有统计学意义(χ2=1.48,P<0.001)。食源性DEC阳性病例的主要的临床症状为单纯性腹泻,所占比例为36.39%(238/950)。其次为腹泻+腹痛,所占比例为22.94%(150/406)。因肉类及其制品为可疑暴露食物所引起的食源性疾病所占比例最高(17.89%)。结论济南市食源性散发腹泻病例DEC感染类型以EAEC为主,全年流行且具有明显的季节性,老年人为易感人群。Objective The study aimed to assess the prevalence of Diarrheagenic Escherichia coli(DEC)in foodborne sporadic diarrhea cases in Jinan.Methods We collected the fecal specimens of diarrhea cases in two hospitals for food-borne disease active surveillance sentinel hospitals in Jinan City from 2014 to 2018.The data of clinical symptom and epidemiological information of the cases were collected.Comparison of rate or composition ratio withχ2 or Fisher exact probability test.Test level was a=0.05.Results In 2014-2018,a total of 2,291 fecal samples of food-borne sporadic diarrhea were collected.The positive rate of DEC was 28.55%(654/2291),of which EAEC positive cases accounted for 60.39%.The male-female ratio was 1.30:1 among 654 DEC-positive cases,and there was no significant difference in the positive rate of DEC between different sexes(χ2=0.118,P=0.731).The positive rate of DEC was highest in M60 group,which was 34.97%(χ2=30.48,P<0.001).The highest positive rate of DEC was in the second quarter,and the positive rate of DEC was statistically significant between different quarters(χ2=1.48,P<0.001).The main clinical symptom of positive DEC cases was only diarrhea,accounting for 36.39%(238/950).Followed by diarrhea+abdominal pain,the proportion was 22.94%(150/406).The highest proportion of foodborne diseases caused by meat and its products(17.89%),which was considered as suspicious food exposure.Conclusion The DEC infection type of foodborne sporadic diarrhea in Jinan City was mainly EAEC,which was popular throughout the year and displayed obvious seasonality.The elderly were the susceptible populations.

关 键 词：食源性疾病 致泻大肠埃希氏菌 临床症状 流行特征 

分 类 号：R117[医药卫生—公共卫生与预防医学]