中频电辅助治疗对老年抑郁症躯体疼痛症状和生活质量的影响  

Auxiliary Effect of Medium Frequency Electrotherapy on Concomitant Pain and Quality of Life for Geriatric Depression

作　　者：王秀艳[1] 王栋 吴伟冬[2] 朱华 WANG Xiuyan;WANG Dong;WU Weidong(Suzhou Guangji Hospital,Suzhou 215000,China)

机构地区：[1]苏州市广济医院,苏州215000 [2]无锡市精神卫生中心

出　　处：《国际精神病学杂志》2019年第6期1016-1019,共4页Journal Of International Psychiatry

基　　金：2017年度无锡市科技发展项目(编号：CSE31N1724)

摘　　要：目的探索中频电治疗联合SSRIs类抗抑郁药对老年抑郁症伴躯体疼痛患者抑郁症状、疼痛症状和生活质量的影响。方法研究组予中频电联合SSRIs类抗抑郁药物,对照组予中频电假刺激联合SSRIs类抗抑郁药物,在基线期、1周、2周、4周评估汉密尔顿抑郁量表(HAMD)、简式McGill疼痛问卷、生活质量量表、副反应量表。结果两组在治疗的第1、2、4周末HAMD得分、疼痛症状得分均比基线期明显减少,通过重复测量方差对比,时间效应,交叉效应显著,在第2、4周末研究组HAMD分值,研究组疼痛分值明显小于对照组,差异均具有显著性(P<0.05)。在第4周末汉密尔顿抑郁量表评分均值显著小于对照组,差异具有显著性(P<0.05)。研究组患者在生活质量躯体健康方面的生理机能、生理职能、躯体疼痛维度评分在治疗4周末显著大于对照组(P<0.05)。结论1.中频电治疗对老年抑郁症伴躯体疼痛患者的抑郁症状、躯体疼痛症状具有明显的增效作用,可显著提高老年抑郁症患者生活质量。Objective To explore the effect of medium frequency electrotherapy(MFET)on depressive symptoms,pain symptoms and quality of life in Geriatric Depression patients with concomitant pain(GDCP).Methods A total of 61 GDCP were recruited from Wuxi mental health center and randomly divided into the treatment group and control group.Treatment group was given MFET and SSRIs therapy.Control group was given SSRIs therapy and sham stimulation regimen.Hamilton depression rating scale(HAMD)and McGill Pain Questionnaire were used to evaluate the severity of depression and pain,at the baseline,1-weekend,2-weekend and 4-weekend of treatment respectively.Short Form 36 Health Survey Questionnaire and Treatment Emergent Symptom Scale were employed at the baseline and 4-week follow-up.Result The change of HAMD index,visual analogous scale(VAS),present pain intensity(PPI),pain rating index(PRI)before and after treatment were all statistically significant.The P value of time effect and the interaction effect are both<0.05,by repeated measure analysis of variance.The change of HAMD index in treatment group was greater than control group at 2-weekend and 4-weekend.The index of HAMD,VAS,PPI,and PRI of treatment group was lesser than control group at the end of 4 weeks.The scores of treatment group were significantly higher than those of the control group after 4 weeks of treatment in terms of physiological function,physiological function and somatic pain dimension(P<0.05).Conclusion As an adjuvant therapy,MFET show significantly auxiliary effect,and improve the quality of life of GDCP.

关 键 词：中频电治疗 老年抑郁症 疼痛症状 生活质量 

分 类 号：R749.05[医药卫生—神经病学与精神病学]