子宫脂肪平滑肌瘤临床及病理学特征探讨(附1例报告及文献复习)  

CLINICAL AND PATHOLOGICAL FEATURES OF UTERINE LIPOLEIOMYOMA: A CASE REPORT AND LITERATURE REVIEW

作　　者：刘婷婷[1] 王翔宇[1] 韩毅[1] 闫伟华[2] 崔竹梅[1] LIU Tingting;WANG Xiangyu;HAN Yi;YAN Weihua;CUI Zhumei(Department of Gynaecology,The Affiliated Hospital of Qingdao University,Qingdao 266100,China)

机构地区：[1]青岛大学附属医院妇科,山东青岛266100 [2]青岛大学附属医院病理科,山东青岛266100

出　　处：《青岛大学学报（医学版）》2020年第1期109-111,共3页Journal of Qingdao University(Medical Sciences)

基　　金：山东省自然科学基金项目(ZR2019MH121)

摘　　要：目的探讨子宫脂肪平滑肌瘤的临床及病理学特征。方法对1例子宫脂肪平滑肌瘤病人的临床资料进行分析,并结合文献探讨子宫脂肪平滑肌瘤的临床及病理特征。结果病人为23岁女性,常规查体发现子宫肌瘤,超声检查怀疑其脂肪变性。行腹腔镜下子宫肌瘤剔除术,术后病理诊断为子宫脂肪平滑肌瘤。子宫脂肪平滑肌瘤病人的临床表现与子宫平滑肌瘤相似。病理检查显示肿瘤由脂肪组织、平滑肌及少量纤维组织构成;免疫组化显示平滑肌肌动蛋白阳性,Ki-67阳性率<1%。结论子宫脂肪平滑肌瘤是一种极为罕见的良性肿瘤,诊断应结合病史、病理形态学特征及免疫组织化学检查结果。Objective To investigate the clinical and pathological features of uterine lipoleiomyoma.Methods The clinical data of one patient with uterine lipoleiomyoma were analyzed,and the clinical and pathological features of uterine lipoleiomyoma were analyzed based on a literature review.Results The 23-year-old female patient was found to have uterine myoma on physical examination,and ultrasound suspected fatty degeneration of uterine myoma.Laparoscopic myomectomy was performed,and the patient was diagnosed with uterine lipoleiomyoma based on postoperative pathology.Patients with uterine lipoleiomyoma had similar clinical manifestations to those with uterine leiomyoma.Pathological examination showed that the tumor was composed of adipose tissue,smooth muscle,and a small amount of fibrous tissue,and immunohistochemistry showed positive smooth muscle actin and a Ki-67 positive rate of<1%.Conclusion Uterine lipoleiomyoma is an extremely rare benign tumor,and diagnosis should be given based on medical history,pathological and morphological features,and immunohistochemistry results.

关 键 词：子宫肿瘤 平滑肌瘤 病理学 临床 

分 类 号：R737.33[医药卫生—肿瘤]