认知行为疗法联合草酸艾司西酞普兰治疗卒中后抑郁的临床效果  

Clinical Effect of Cognitive Behavioral Therapy Combined with Escitalopram Oxalate in the Treatment of Post-stroke Depression

作　　者：郭慧 崔子昂 焦鸿云[3] GUO Hui;CUI Zi-ang;JIAO Hong-yun(Department of Neurology,Beijing Jingmei Group General Hospital,Beijing 102300,China;Department of Internal Medicine,Beijing Jingmei Group General Hospital,Menkuang Branch,Beijing 102300,China;Psychosomatic Clinic of Beijing Jingmei Group General Hospital,Beijing 102300,China)

机构地区：[1]北京京煤集团总医院神经内科,北京102300 [2]北京京煤集团总医院门矿分院内科,北京102300 [3]北京京煤集团总医院心身门诊,北京102300

出　　处：《医学信息》2020年第4期121-122,共2页Journal of Medical Information

摘　　要：目的探讨认知行为疗法联合草酸艾司西酞普兰治疗卒中后抑郁的临床效果。方法选择2016年2月~2019年2月我院收治的卒中后抑郁患者84例,采用随机数字表法分为研究组和对照组,各42例。对照组采用草酸艾司西酞普兰治疗,研究组在对照组基础上联合认知行为疗法治疗,两组均持续治疗8周。比较两组治疗前后认知功能及抑郁程度评分。结果研究组治疗后认知功能评分为(24.15±4.11)分,高于对照组的(20.93±4.40)分,差异有统计学意义(P<0.05);研究组治疗后抑郁程度评分为(8.23±3.14)分,低于对照组的(11.15±4.06)分,差异有统计学意义(P<0.05)。结论认知行为疗法联合草酸艾司西酞普兰治疗卒中后抑郁疗效确切,有助于改善患者认知功能,减轻抑郁程度,值得临床应用。Objective To investigate the clinical effect of cognitive behavioral therapy combined with escitalopram oxalate in the treatment of post-stroke depression.Methods 84 patients with post-stroke depression treated in our hospital from February 2016 to February 2019 were selected and divided into a study group and a control group by random number table,with 42 cases in each group.The control group was treated with escitalopram oxalate.The study group was combined with cognitive behavioral therapy based on the control group.Both groups continued to treat for 8 weeks.The scores of cognitive function and depression degree before and after treatment were compared between the two groups.Results The cognitive function score of the study group after treatment was(24.15±4.11)points,which was higher than that of the control group(20.93±4.40)points,the difference was statistically significant(P<0.05).The depression score of the study group after treatment was(8.23±3.14)points,which was lower than that of the control group(11.15±4.06)points,the difference was statistically significant(P<0.05).Conclusion Cognitive behavioral therapy combined with escitalopram oxalate is effective in treating post-stroke depression,and it is helpful to improve patients'cognitive function and reduce the degree of depression.It is worthy of clinical application.

关 键 词：卒中后抑郁 认知行为疗法 草酸艾司西酞普兰 认知功能 抑郁程度 

分 类 号：R743.3[医药卫生—神经病学与精神病学]