肠易激综合征发病机制研究进展  

Research advances in the pathogenesis of irritable bowel syndrome

作　　者：曾灏瑜 白涛[1] 侯晓华[1] ZENG Hao-yu;BAI Tao;HOU Xiao-hua(Department of Gastroenterology,Union Hospital Affiliated to Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430022,China)

机构地区：[1]华中科技大学同济医学院附属协和医院消化内科,湖北武汉430022

出　　处：《中国实用内科杂志》2020年第2期115-118,共4页Chinese Journal of Practical Internal Medicine

摘　　要：肠易激综合征(irritable bowel syndrome,IBS)是常见的功能性肠病,以腹痛伴有大便性状和排便习惯改变为主要表现。IBS发病机制复杂,包括了增加IBS易感性的因素及与症状发作相关的因素,多种因素相互作用导致了相应的病理生理变化,从而产生IBS症状,文章就已有的研究结果对IBS的发病机制进行总结。Irritable bowel syndrome(IBS)is a prevalent functional bowel disease characterized by abdominal pain with changes in the habits of bowel movement.The pathogenesis of IBS is so complicated,including factors increasing the susceptibility of IBS and related to the occurence of symptoms.The interaction of various factors leads to the corresponding pathophysiological changes and results in IBS symptoms.This article summarizes the pathogenesis of IBS based on the current researches.

关 键 词：肠易激综合征 发病机制 动力异常 内脏高敏感性 

分 类 号：R574.4[医药卫生—消化系统]