胃充盈状态对18F-FDG PET/CT图像质量的影响  

The Influence of Gastric-Filling on PET/CT Image Quality and Lesion Detectability

作　　者：王华涛[1] 赵葵[1] 张亚飞[1] 王国林[1] 赵欣[1] 颜京 诸欢燕[1] WANG Huatao;ZHAO Kui;ZHANG Yafei(PET center,The First Affiliated Hospital of Medical School of Zhejiang University,Hangzhou 310003,Zhejiang Province,P.R.China)

机构地区：[1]浙江大学医学院附属第一医院PET中心

出　　处：《临床放射学杂志》2019年第12期2425-2428,共4页Journal of Clinical Radiology

摘　　要：目的探讨胃充盈状态对PET/CT图像质量的影响以及对胃部占位性疾病的诊断价值。方法对80例首次行PET/CT时胃充盈欠佳的患者再次行胃部PET/CT,测定两次显像胃部病灶的最大标准摄取值(SUVmax),计算两次显像SUVmax的差值(ΔSUVmax)。结果胃部良性病变组SUV充盈前=4.32±1.93,SUV充盈后=3.68±1.23,ΔSUV胃部良性病变组=-0.48±1.18;胃部恶性病变组SUV充盈前=4.28±2.20,SUV充盈后=4.96±2.61,ΔSUV胃部恶性病变组=0.63±1.00;胃充盈后,胃部恶性病变组的ΔSUVmax升高幅度明显高于胃部良性病变组(P<0.01)。非胃部良性病变组SUV充盈前=3.38±0.98,SUV充盈后=2.73±1.19,ΔSUV非胃部良性病变组=-0.65±0.98;非胃部恶性病变组SUV充盈前=4.29±2.34,SUV充盈后=3.93±2.45,ΔSUV非胃部恶性病变组=-0.36±1.10;胃充盈后,非胃部恶性病变的SUVmax升高幅度与良性病变组无明显差异(P=0.36)。结论胃部恶性病变组SUV充盈后升高幅度明显高于胃部良性病变组,但非胃部恶性病变组SUV充盈后升高幅度与非胃部良性病变组无明显差异;胃腔充盈后行PET/CT,能更清晰地显示胃部病灶,有利于提高胃部病灶的检出率,同时减少胃部假阳性病灶诊断。Objective To explore the value of gastric-filling on PET/CT image quality and lesion detectability.Meth-ods A total of 80 patients,who underwent stomach PET/CT scan twice,were retrospectively analyzed in this study.For each patient,the stomach was empty during the first PET scan while the second PET scan had gastric filling.The maximum standardized uptake value(SUVmax)and SUV variation(ΔSUV)of PET/CT imaging was calculated for the two-time points.Results TheΔSUVmax of benign gastric lesion group and gastric cancer group was-0.48±1.18 and 0.63±1.00,respectively,with significant difference between them(P<0.01).TheΔSUVmax of benign non-gastric lesion group and non-gastric cancer group was-0.65±0.98 and-0.36±1.10,respectively,and there is no significant difference between them(P=0.36).Conclusion The SUVmax increased greatly in the gastric cancer group compared with the be-nign gastric lesion group.There is no difference of SUVmax changes between the benign non-gastric lesion group and the non-gastric cancer group.Thus,PET/CT imaging with gastric-filling could clearly display gastric lesions and is useful in the differential diagnosis of benign and malignant diseases of the stomach.

关 键 词：正电子发射断层显像 氟代脱氧葡萄糖18F 胃癌 

分 类 号：R573[医药卫生—消化系统] R817.4[医药卫生—内科学]