保留皮肤的乳腺癌改良根治术后即刻乳房再造与改良根治术的效果比较  

Comparison of the Effect of Immediate Breast Reconstruction after Skin Preserving Modified Radical Mastectomy and Modified Radical Mastectomy

作　　者：许子志 黄国聪 许东兴 XU Zizhi;HUANG Guocong;XU Dongxing(Putian First Hospital,Putian 351100,China)

机构地区：[1]莆田市第一医院

出　　处：《中外医学研究》2020年第4期133-135,共3页CHINESE AND FOREIGN MEDICAL RESEARCH

摘　　要：目的:探究保留皮肤的乳腺癌改良根治术后即刻乳房再造与改良根治术的治疗效果。方法:将2011年4月-2014年6月入院就诊的100例乳腺癌患者为研究对象,根据手术方法不同将其划分为对照组和观察组,每组50例。对照组予以改良根治术治疗,观察组行保留皮肤的乳腺癌改良根治术后即刻乳房再造。比较两组患者术后并发症情况、5年总生存率、5年无病生存率及生活质量。结果:两组患者术后皮下积液、皮瓣坏水及上肢水肿等并发症发生率比较,差异无统计学意义(P>0.05);两组5年总生存率及无病生存率比较,差异无统计学意义(P>0.05);观察组生活质量评分高于对照组,差异均有统计学意义(P<0.05)。结论:实施保留皮肤的改良根治术后即刻乳房再造的方式与改良根治术疗效相当,术后并发症发生率较低、5年生存率及5年无病生存率均较高。但保留皮肤的改良根治术后即刻乳房再造可提升术后患者生活质量,临床价值显著,值得推广。Objective: To investigate the therapeutic effects of immediate breast reconstruction after skin preserving modified radical mastectomy and modified radical mastectomy. Method: A total of 100 cases of breast cancer patients admitted to hospital from April 2011 to June 2014 were selected as the study subjects. According to different surgical methods, they were divided into the control group and the observation group, with 50 cases in each group. The control group was treated with modified radical mastectomy, and the observation group was treated with immediate breast reconstruction after skin preserving modified radical mastectomy. The postoperative complications, 5-year overall survival rate, 5-year disease-free survival rate and quality of life were compared between the two groups. Result: There were no significant differences in the incidence of postoperative complications such as subcutaneous hydrops, skin flap bad water and upper extremity edema between the two groups(P>0.05). There were no significant differences in the 5-year overall survival rate and 5-year disease-free survival rate between the two groups(P>0.05). The quality of life scores of the observation group were higher than those of the control group, and the differences were statistically significant(P<0.05). Conclusion: Immediate breast reconstruction after skin preserving modified radical mastectomy is as effective as modified radical mastectomy, with lower incidence of postoperative complications, higher 5-year survival rate and 5-year disease-free survival rate. However, immediate breast reconstruction after skin preserving modified radical mastectomy can improve the quality of life of patients after operation, which has significant clinical value and is worth popularizing.

关 键 词：乳腺癌 即刻乳房再造 保留皮肤 改良根治术 效果 

分 类 号：R737.9[医药卫生—肿瘤]