肠道菌群失调在肝癌发生、发展和预防、治疗中的研究进展  

Advances in Research on Intestinal Flora Imbalance in the Development and Prevention of Liver Cancer

作　　者：雷中利 黄燕[1] LEI Zhongli;HUANG Yan(Oncology Department,the Dazu District People’s Hospital,Chongqing,402360,China)

机构地区：[1]重庆医科大学附属第一医院大足医院/重庆市大足区人民医院肿瘤科

出　　处：《肿瘤药学》2020年第1期16-20,共5页Anti-Tumor Pharmacy

基　　金：重庆市科技计划项目(2016017)

摘　　要：肝细胞癌是全球恶性肿瘤死亡的第三大原因。药物滥用、肝毒素摄取(如黄曲霉毒素)、饮酒以及病毒性肝炎等是肝癌发生的主要危险因素。然而,越来越多的研究表明,肠道菌群失调在促进肝癌发展过程中也起着关键作用。本文就肠道菌群失调在肝癌发生、发展过程中以及预防和治疗方面的最新进展作一综述。Hepatocellular carcinoma is the third leading cause of death in malignant tumors worldwide.Drug abuse,hepatic toxin intake(such as aflatoxin),drinking,and viral hepatitis are major risk factors for liver cancer.However,more and more studies have shown that intestinal flora imbalance also plays a key role in promoting the development of liver cancer.Therefore,this article reviews the recent progress of intestinal flora imbalance in the occurrence,development and treatment of liver cancer.

关 键 词：肠道菌群失调 肝癌 研究进展 

分 类 号：R735.7[医药卫生—肿瘤]