癌症患儿神经性疼痛治疗进展  

Progress in the treatment of neuropathic pain in children with cancer

作　　者：周蕾 周泽军[1] Zhou Lei;Zhou Zejun(Department of Anesthesiology,the First Affiliated Hospital of Chongqing Medical University,Chongqing 400016,China)

机构地区：[1]重庆医科大学第一附属医院麻醉科

出　　处：《现代肿瘤医学》2020年第5期867-870,共4页Journal of Modern Oncology

基　　金：卫生部国家临床重点专科建设项目[编号:财社(2011)170号];重庆市医学重点学科项目[编号:渝卫科教(2007)2]

摘　　要：癌性神经性疼痛是指由于损害或疾病直接影响躯体感觉系统而产生的疼痛;当然,并不是所有躯体感觉系统受损都会导致神经性疼痛。在儿童癌症患者中,引起神经性疼痛原因有多种,如化疗药(如长春新碱、顺铂和紫杉醇等)、脊髓损伤、肿瘤对组织及神经的直接损伤等。神经性疼痛发生率虽低于躯体性疼痛,但其更难治疗,需要更多的临床随访,更复杂的用药管理,以及频繁的非药物干预。为了更好地控制癌症患儿神经性疼痛,本文拟对癌症患儿神经性疼痛的治疗方法进行综述,以更好地指导临床治疗。Cancer pain can be divided into two types:Somatic pain and neuropathic pain.The international association for the study of pain defines neuropathic pain as pain caused by damage or disease that directly affects the somatosensory system.However,not all somatosensory impairment causes neuropathic pain.In pediatric cancer patients,neuropathic pain is caused by a variety of reasons,such as chemotherapy drugs(such as vincristine,cisplatin and paclitaxel,et al),spinal cord injury,and direct injury of tumor to tissues and nerves.The incidence of neuropathic pain is lower than that of somatic pain,but it is more difficult to treat,requiring more clinical follow-up,more complex drug administration,and frequent non-drug interventions.In order to better solve the neuropathic pain in children with cancer,this paper intends to review the treatment methods of neuropathic pain in children with cancer,so as to better guide clinical treatment.

关 键 词：癌痛 儿童 药物治疗 介入治疗 

分 类 号：R730.6[医药卫生—肿瘤]