丝氨酸/甘氨酸代谢在肿瘤中的研究进展  

The progress of serine/glycine metabolism in tumor

作　　者：马瑞肖 张慧杰[1] 李馨慧 张淑兰[1] Ma Ruixiao;Zhang Huijie;Li Xinhui;Zhang Shulan(Department of Obstetrics and Gynecology,Shengjing Hospital of China Medical University,Liaoning Shenyang 110004,China)

机构地区：[1]中国医科大学附属盛京医院妇产科

出　　处：《现代肿瘤医学》2020年第6期1021-1024,共4页Journal of Modern Oncology

摘　　要：丝氨酸/甘氨酸代谢具有提供一碳单位,合成其他氨基酸、核苷酸、脂质以及合成还原性物质使细胞内氧化还原处于动态平衡状态等作用,在生物代谢中很重要;近年来,研究表明丝氨酸/甘氨酸代谢在肿瘤中起至关重要的作用,影响着肿瘤的发生发展过程和治疗效果。现就丝氨酸/甘氨酸代谢在肿瘤中的研究作一综述。Serine/glycine metabolism plays an important role in biological metabolism by providing one-carbon unit,synthesis of other amino acids,nucleotides and lipid,and synthesizing reducing substances to maintain the balance of cell redox.In recent years,a large number of studies have shown that serine/glycine metabolism plays a crucial role in tumor's development and treatment.The studies of serine/glycine metabolism in tumors were reviewed.

关 键 词：丝氨酸/甘氨酸代谢 肿瘤 治疗 

分 类 号：R730.231[医药卫生—肿瘤]