常州地区青少年人群不同代谢综合征诊断标准的比较研究  

A comparative study of the different diagnostic criteria for metabolic syndrome among adolescents in Changzhou area

作　　者：肖扬 徐书杭[1] 黄华英[2] 郭玲 吕文君[2] 冯宁霞[2] 汪奇峰 茅晓东[1] 陈国芳[1] 刘超[1] Xiao Yang;Xu Shuhang;Huang Huaying;Guo Ling;Lyu Wenjun;Feng Ningxia;Wang Qifeng;Mao Xiaodong;Chen Guofang;Liu Chao(Department of Endocrinology,Affiliated Hospital of Integrated Traditional Chinese and Western Medicine,Nanjing University of Chinese Medicine,Jiangsu Province Academy of Traditional Chinese Medicine,Nanjing 210028,China;Department of Endocrinology,Chinese Medical Hospital of Wujin,Changzhou 213100,China)

机构地区：[1]南京中医药大学附属中西医结合医院(江苏省中医药研究院)内分泌科,210028 [2]常州市武进中医医院内分泌科,213100

出　　处：《国际内分泌代谢杂志》2020年第1期1-4,共4页International Journal of Endocrinology and Metabolism

基　　金：常州市武进区科技项目(WS201617);国家重点研发计划(2016YFC1305202)。

摘　　要：目的探讨不同诊断标准对青少年代谢综合征(MS)患病率及各组分检出率的影响。方法选取江苏省常州市1097名12~15岁青少年学生(男生占55.6%),进行体格检查和生化检测;选取3种青少年MS诊断标准,即中华医学会儿科分会推荐的儿童、青少年MS诊断标准(中国标准)、2007年国际糖尿病联盟推荐的诊断标准(IDF标准)和2003年Cook等参照美国国家胆固醇教育计划制定的诊断标准(Cook标准)对受试者进行诊断;分析中国标准对不同性别青少年人群MS及各组分的检出率;比较3种不同诊断标准下的青少年MS患病率、各组分检出率的差异。结果中国标准检出的青少年MS患病率男性显著高于女性(χ^2=9.574,P=0.002)。MS组分中,男性肥胖(χ^2=30.211,P<0.01)、高血压、高血糖、低高密度脂蛋白-胆固醇血症的检出率均高于女性。中国标准检出率最高的MS组分是高甘油三酯血症(χ^2=177.34,P<0.01),而IDF标准(χ^2=237.43,P<0.01)和Cook标准(χ^2=352.11,P<0.01)检出率最高的均为高血压。结论3种诊断标准对青少年MS总体患病率的检出结果差别较小,而对MS各组分检出率差别显著。Objective To explore the impact of different diagnostic criteria on the prevalence of metabolic syndrome(MS)and the detection rate of its components among adolescents.Methods A total of 1097 middle school students aged between 12-15 years old(55.6%males)in Changzhou area of Jiangsu Province were enrolled.All the participants underwent physical examination and biochemical test,and MS was diagnosed with 3 different criteria:children and teenagers MS diagnostic criteria recommended by Pediatric Academy of Chinese Medical Association(Chinese criteria),the International Diabetes Federation criteria in 2007(IDF criteria)or Cook criteria based on the National Cholesterol Education Program-Adult Treatment Panel in 2003(Cook criteria).The detection rate of MS and its components in adolescent population of different genders were analyzed with Chinese criteria,and also the detection rate of teenage MS and its components were compared under three different diagnostic criteria.Results The detection rate of teenage MS in male was significantly higher than that in female with Chinese criteria(χ^2=9.574,P=0.002).Among the components of MS,the detection rate of obesity(χ^2=30.211,P<0.01),hypertension,hyperglycemia,and low high-density lipoprotein-cholesterol in male subjects were all higher than those in female subjects.The component with the highest incidence was hypertriglyceridemia with Chinese criteria(χ^2=177.34,P<0.01),and hypertension with IDF criteria(χ^2=237.43,P<0.01)and Cook criteria(χ^2=352.11,P<0.01).Conclusions Three diagnostic criteria show little difference in the overall prevalence of MS among teenagers.However,the detection rate of MS components are evidently different with three criteria.

关 键 词：青少年 代谢综合征 诊断标准 

分 类 号：R72[医药卫生—儿科]