脑心通胶囊联合等速肌力训练治疗脑卒中偏瘫临床研究  

Clinical Study on Naoxintong Capsules Combined with Isokinetic Exercise for Hemiplegia after Stroke

作　　者：魏博[1] 杜烨 沈晶晶 WEI Bo;DU Ye;SHEN Jingjing

机构地区：[1]绍兴市人民医院

出　　处：《新中医》2020年第2期64-67,共4页New Chinese Medicine

摘　　要：目的:观察分析脑心通胶囊与常规西药联合等速肌力训练治疗脑卒中偏瘫的临床疗效。方法:将脑卒中偏瘫患者200例,按数字奇偶法分为研究组与对照组各100例,2组均临床给予等速肌力训练治疗,对照组在此基础上给予替扎尼定治疗,研究组在对照组基础上加用脑心通胶囊治疗,连续治疗4周后观察2组临床疗效。结果:治疗前,2组血浆纤维蛋白原(FIB)、凝血酶原时间(PT)、凝血时间(TT)及活化部分凝血酶时间(APTT)水平比较,差异无统计学意义(P>0.05)。治疗后,2组FIB、PT、TT、APTT水平较治疗前升高,且研究组FIB、PT、TT、APTT水平升高幅度大于对照组(P<0.05)。治疗前,2组简式Fugl-Meyer运动功能评分法(FMA)、改良Barthel指数(MBI)评分比较,差异无统计学意义(P>0.05)。治疗后,2组FMA、MBI评分较治疗前升高,且研究组FMA、MBI评分升高幅度大于对照组(P<0.05)。治疗后,研究组总有效率为89.00%,对照组总有效率为66.00%,2组比较,差异有统计学意义(P<0.05)。结论:脑卒中偏瘫患者实施脑心通胶囊与常规西药联合等速肌力训练治疗疗效确切,可有效改善患者凝血功能,有效恢复患者肢体运动功能及提高日常生活活动能力。Objective:To observe and analyze the clinical effect of Naoxintong capsules and routine western medicine combined with isokinetic exercise for hemiplegia after stroke.Methods:A total of 200 cases of patients with hemiplegia after stroke were divided into the study group and the control group according to the odd-even number grouping method,100 cases in each group.Both groups were treated with clinical isokinetic exercise;the control group was additionally treated with tizanidine,and the study group was additionally treated with Naoxintong capsules based on the treatment of the control group.After treatment for four weeks,the clinical effect in the two groups was observed.Results:Before treatment,compared with the levels of fibrinogen(FIB),prothrombin time(PT),thrombin time(TT)and activated partial thromboplastin time(APTT),there was no significance in the difference(P>0.05).After treatment,the levels of FIB,PT,TT and APTT in the two groups were increased when compared with those before treatment,and the improvement of the above levels in the study group was larger than that in the control group(P<0.05).Before treatment,compared with the scores of short-form Fugl-Meyer Assessment(FMA)and Modified Barthel Index(MBI)in the two groups,there was no significance in the difference(P>0.05).After treatment,the scores of FMA and MBI in the two groups were increased when compared with those before treatment,and the improvement of the above two scores in the study group was larger than that in the control group(P<0.05).After treatment,the total effective rate was 89.00%in the study group and 66.00%in the control group,the difference being significant(P<0.05).Conclusion:The therapy of Naoxintong capsules and routine western medicine combined with isokinetic exercise has exact curative effect in treating patients with hemiplegia after stroke,which can effectively improve their coagulation function and activities of daily living,and recover their extremity motor function.

关 键 词：脑卒中 偏瘫 脑心通胶囊 等速肌力训练 凝血功能 简式Fugl-Meyer运动功能评分法(FMA) 改良Barthel指数(BMI) 

分 类 号：R743.3[医药卫生—神经病学与精神病学]