Metal-Carbene-TempIated Photochemistry in Solution: A Universal Route towards Cyclobutane Derivatives  

作　　者：Yang Li Guang-Feng Jin Yuan-Yuan An Rajorshi Das Ying-Feng Han 

机构地区：[1]Key Laboratory of Synthetic and Natural Functional Molecule Chemistry,College of Chemistry and Materials Science,Northwest University,Xi'an,Shaanxi 710127,China

出　　处：《Chinese Journal of Chemistry》2019年第11期1147-1152,I0002,共7页中国化学（英文版）

摘　　要：Background and Originality Content Cyclobutane moieties are an important class of motifs since they are frequently found in the medicinally relevant compounds such as alkaloids and pharmaceuticals.[1] Therefore,the develop­ment of efficient synthetic strategies for the construction of cy­clobutanes and their derivatives has always been a focus of inter-est.[2a] Photochemical reactions are powerful tools for synthesiz­ing compounds with high complexity and diversity.[2b-h] Among them,photochemical[2+2]cycloaddition is a widely used proto­col for the preparation of such compounds.[2h]However,this kind of reaction always suffers from the challenges of controlling the resulting products of the intermolecular[2+2]photodimerization.In principle,to achieve cyclobutanes via[2+2]cycloaddition,the two olefins should be oriented in a parallel fashion keeping the distance less than 4.2 A apart from each other.

关 键 词：BUTANE PHOTOCHEMICAL ALKALOIDS 

分 类 号：O62[理学—有机化学]