贲门失弛缓症的病因和治疗进展  

Research Progress on Etiology and Treatment of Achalasia

作　　者：张莉莉[1] 王彬[1] 晋弘[1] 赵威[1] 王邦茂[1] ZHANG Lili;WANG Bin;JIN Hong;ZHAO Wei;WANG Bangmao(Department of Gastroenterology, Tianjin Medical University General Hospital, Tianjin ,300052)

机构地区：[1]天津医科大学总医院消化内科

出　　处：《胃肠病学》2019年第12期745-749,共5页Chinese Journal of Gastroenterology

基　　金：国家自然科学基金青年科学基金项目(81600425)

摘　　要：贲门失弛缓症是一种食管动力障碍性疾病,年发病率约为1/10万,但近年来其发病率有上升趋势。该病临床上表现为吞咽困难、胸骨后疼痛、食物反流等症状,严重者可诱发食管癌甚至猝死,严重影响患者生活质量。目前贲门失弛缓症的病因尚不明确,现有治疗方法优、缺点各异。本文就近年来贲门失弛缓症病因和治疗手段的研究进展作一综述。Achalasia is an esophageal motility disorder with an annual incidence of about 1/10000,and the incidence has been increasing in recent years.The clinical manifestations include dysphagia,chest pain,and regurgitation,etc.Achalasia seriously affects the patient’s quality of life,and the severe disease may increase the risk of esophageal carcinoma or even be life threatening with sudden death.At present,the etiology of achalasia is not fully clarified,and the advantages and disadvantages of various treatment modalities are different.This article summarized the research progress on etiology and treatment of achalasia in recent years.

关 键 词：食管失弛症 病因学 治疗 

分 类 号：R73[医药卫生—肿瘤]