碘难治性分化型甲状腺癌的精准靶向治疗进展  

Research progress in accurate targeted therapy for radioiodine refractory differentiated thyroid cancer

作　　者：王新霞 马腾闯 崔亚利[1] Wang Xinxia;Ma Tengchuang;Cui Yali(Department of Nuclear Medicine,Harbin Medical University Cancer Hospital,Harbin 150081,China)

机构地区：[1]哈尔滨医科大学附属肿瘤医院核医学科,150081

出　　处：《国际放射医学核医学杂志》2019年第6期569-575,共7页International Journal of Radiation Medicine and Nuclear Medicine

基　　金：黑龙江省科学基金(QC2017113);哈尔滨医科大学肿瘤医院海燕科研基金(JJZD2018-02)。

摘　　要：甲状腺癌的发病率逐年上升,传统的治疗方法对于碘难治性分化型甲状腺癌的疗效有限。靶向治疗是近年来比较热门的新型治疗方法,在甲状腺癌的治疗上已取得一定研究成果。笔者就碘难治性分化型甲状腺癌的精准靶向治疗策略——药物靶向治疗、肽受体核素靶向治疗、局部精准治疗以及免疫治疗进行综述。The incidence of thyroid cancer is increases year by year.Traditional treatment for radioiodine refractory differentiated thyroid cancer is limited.Targeted therapy is a popular new treatment method in recent years,and has achieved positive results in the treatment of thyroid carcinoma.This article reviews the accurate targeting therapy strategy of radioiodine refractory differentiated thyroid carcinoma,drug targeting therapy,peptide receptor radionuclide targeting therapy,local precise therapy and immunotherapy.

关 键 词：碘难治性分化型甲状腺癌 免疫疗法 靶向治疗 核素靶向治疗 

分 类 号：R73[医药卫生—肿瘤]