纳米氧化锌改性复合树脂即刻抗菌性能及其机制的研究  

The immediate antibacterial property and the mechanism of nano-ZnO modified composite resin

作　　者：梁蓓蕾[1] 逯宜[1] 李蕴聪[1] 刘瑞瑞[1] LIANG Beilei;LU Yi;LI Yuncong;LIU Ruirui(Key Laboratory of Shaanxi Province for Craniofacial Precision Medicine Research,Stomatology Hospital,Xi'an Jiaotong University,710004)

机构地区：[1]陕西省颅颌面精准医学研究重点实验室,西安交通大学口腔医院,710004

出　　处：《实用口腔医学杂志》2020年第1期20-23,共4页Journal of Practical Stomatology

基　　金：陕西省自然科学基金青年项目(编号:2018JQ8072);中央高校基本科研业务费专项资金(编号:08143012)。

摘　　要：目的:研究nano-ZnO改性对复合树脂即刻抗菌性能的影响,并对其抗菌机制进行初步的探索。方法:采用直接接触法检测nano-ZnO改性对复合树脂即刻抗菌(变形链球菌)性能的影响,用Zn试剂盒测定固化后nano-ZnO改性复合树脂浸析液中锌离子的浓度。结果:nano-ZnO添加量(%)为1、5和10时改性复合树脂的即刻抗菌率(%)分别为1.75±6.87、67.35±3.76和77.44±4.55(P<0.05),其锌离子释放量也明显增加(P<0.05)。结论:nano-ZnO改性能够为复合树脂赋予抗菌活性,并且这一抗菌性能可能与锌离子的释放有关。Objective:To investigate the immediate effects of nano-ZnO modification on the antibacterial properties of the composite resin,and the antibacterial mechanism.Methods:Direct contact method was used to evaluate the immediate effect of nano-ZnO modification on the antibacterial activity of the composite resin against S.mutans,the concentration of zinc ions released from the resin was measured by Zn kit.Results:The resin samples with nano-ZnO(%)of 1,5 and 10,inhited the S.mutans the colony formation(%)by 1.75±6.87,67.35±3.76 and 77.44±4.55 respectively(P<0.05),with the increase of nano-ZnO content in the resin the zinc ion release of the modified composite resin increased obviously(P<0.05).Conclusion:The modification of nano-ZnO can impart antibacterial activity of the composite resin,and this may be associated with the release of zinc ions.

关 键 词：复合树脂 纳米氧化锌 抗菌性 

分 类 号：R783.1[医药卫生—口腔医学]