儿童布氏杆菌病14例临床分析  

Clinical analysis of 14 children with Brucellosis

作　　者：王艳春[1] 黄海林[1] 张青 周玲[1] 杨小涛[1] Wang Yanchun;Huang Hailin;Zhang Qing;Zhou Ling;Yang Xiaotao(Second Department of Infectious Disease,Kunming Children’s Hospital,Kunming 650034,China)

机构地区：[1]云南省昆明市儿童医院感染二科,650034

出　　处：《中国实用医刊》2019年第24期20-22,共3页Chinese Journal of Practical Medicine

摘　　要：布氏杆菌病是由布氏杆菌引起的一种人畜共患疾病,羊、牛等疫畜是其主要传染源。布氏杆菌是一种革兰阴性小球杆菌,共有6个生物种,其中羊种致病力最强,可经破损的皮肤黏膜、消化道和呼吸道等途径传播。布氏杆菌病在我国主要流行于牧区,云南省为非牧区,布氏杆菌病发病率较低,临床医师对布氏杆菌病认识不足,临床易误诊。此14例布氏杆菌病患儿均为羊种布氏杆菌感染,均有羊接触史。14例患儿确诊布氏杆菌感染后,依据年龄和病情给予相应抗生素足疗程治疗,均治愈,随访1年无复发。儿童布氏杆菌感染临床表现多样,易误诊,详细询问流行病学史,尤其是与牛羊接触的病史,尽早完善血培养、骨髓培养及布氏杆菌抗体检测是明确诊断的关键。Brucellosis is a zoonotic disease caused by Brucella.The main source of infection are sheep and cattle.Brucella is a Gram-negative coccobacillus belonging to 6 species,of which the sheep are the most pathogenic,and spread through damaged skin mucosa,digestive tract and respiratory tract.Brucellosis is mainly prevalent in pastoral areas in China.Yunnan is a non-pastoral area,the incidence of Brucellosis is low,clinicians have insufficient understanding of Hrucellosis,and clinical misdiagnosis.All 14 children were infected with Brucella,and all of them had a history of exposure to sheep.After 14 cases of Brucella infection were diagnosed,the corresponding antibiotics were given according to age and condition.And all patients were cured.There was no recurrence after 1 year of follow-up.The clinical manifestations of Brucella infection in children are diverse and easy to be misdiagnosed.The history of epidemiology,especially history of contact with cattle and sheep,and improvement of blood culture,bone marrow culture and Brucella antibody detection as early as possible are the key to the diagnosis.

关 键 词：布氏杆菌病 小球杆菌 足疗程 

分 类 号：R73[医药卫生—肿瘤]