人乳头瘤病毒感染与生殖器病变关系的研究进展  

Advancesin research on the relationship between human papilloma-virus infection and genital lesions

作　　者：张仕华[1] 孙辉[1] 杜彦丹[1] ZHANG Shihua;SUN Hui;DU Yandan(Department of Laboratory,Inner Mongolia Forestry General Hospitalthe Second Clinical Medicine College of Inner Mongolia University for Nationalities,Inner Mongolia Autonomous Region,Yakeshi022150,China)

机构地区：[1]内蒙古林业总医院内蒙古民族大学第二临床医学院检验科

出　　处：《中国医药导报》2020年第4期48-51,共4页China Medical Herald

基　　金：内蒙古自治区卫生计生科研计划项目（201703192）;内蒙古民族大学国家基金培育项目（NMDGP17108）

摘　　要：人乳头瘤病毒(HPV)根据致病性可分为高危型和低危型。高危型主要导致女性宫颈癌和男性阴茎癌,低危型主要引起生殖器疣。不同基因型所致疾病类型有一定的差异,女性鳞癌以HPV-16为主要型别;女性腺癌和腺鳞癌以HPV-18为主;男性阴茎癌以HPV-16、HPV-18感染为主;女性生殖器疣和男性生殖器疣、不孕症以HPV-6、HPV-11为主要型别。目前市场上针对HPV有预防性和治疗性两种疫苗,不同人群应有针对性地合理选择疫苗,对预防和清除HPV至关重要。Human papillomavirus(HPV)can be divided into high-risk type and low-risk type according to pathogenicity.The high-risk type mainly causes cervical cancer in women and the penis cancer in men,while the low-risk type mainly causes genital warts.Different genotypes cause certain differences in disease types.HPV-16 is the main type of female squamous cell carcinoma;HPV-18 is the main type of female adenocarcinoma and adenosquamous carcinoma;HPV-16 and HPV-18 infection are the main types of male penile cancer;the main types of female genital warts and male genital warts and infertility are HPV-6 and HPV-11.Currently,there are two preventive and therapeutic vaccines for HPV on the market.Different populations should choose vaccines in a targeted and reasonable manner,which is essential for preventing and eliminating HPV.

关 键 词：人乳头瘤病毒感染 生殖系统肿瘤 生殖器疣 亚型 

分 类 号：R737.33[医药卫生—肿瘤]