RFTVR术、新型光纤CO2激光术对早期喉癌患者症状改善情况和QOL评分、VAS评分的影响  

Effects of RFTVR and CO2 laser on symptoms improvement, QOL and vas of patients with early laryngeal cancer

作　　者：刘婷 陈仁杰[1] 庄晓玲[2] 庄汉[2] 刘冰[3] LIU Ting;CHEN Ren-jie;ZHUANG Xiao-ling;ZHUANG Han;LIU Bing(Department of Otolaryngology, Second Affiliated Hospital of Nanjing Medical University, Nanjing Jiangsu, 210011 China;Department of Otolaryngology, Suqian People's Hospital, Nanjing Drum Tower Hospital Group, Suqian Jiangsu, 223800 China;Department of Otolaryngology, Xuzhou Central Hospital, Xuzhou Jiangsu, 221000 China)

机构地区：[1]南京医科大学第二附属医院耳鼻咽喉科,江苏南京210011 [2]南京鼓楼医院集团宿迁市人民医院耳鼻咽喉科,江苏宿迁223800 [3]徐州市中心医院耳鼻喉科,江苏徐州221000

出　　处：《海南医学院学报》2020年第5期359-362,共4页Journal of Hainan Medical University

基　　金：医学免疫学国家重点实验室开放课题NKMI2019K07~~

摘　　要：目的:研究RFTVR术、新型光纤CO2激光术对早期喉癌患者症状改善情况和QOL评分、VAS评分的影响。方法:选择2015年1月~2016年12月诊断治疗的喉癌患者120例作为研究对象,随机分为观察组和对照组各60例,观察组采取RFTVR术治疗,对照组采取新型光纤CO2激光术治疗。比较两组围手术期指标、吞咽功能、发音功能、生存期、QOL评分、VAS评分之间的差异。结果:两组术中出血量、手术时间以及住院时间之间比较,差异无统计学意义(P>0.05);观察组无误咽情况高于对照组,经过治疗后,两组jitter、shimmer、HNR均明显改善,且观察组jitter、shimmer低于对照组,HNR高于对照组(P<0.05);两组QOL评分、VAS评分均明显改善,且观察组的QOL评分高于对照组、VAS评分低于对照组(P<0.05);观察组的总生存期以及无瘤生存期高于对照组。结论:相比CO 2激光治疗,低温等离子射频消融手术治疗的患者吞咽功能以及发音功能明显改善,同时通过对患者生存期的延长,改善患者的生命质量。Objective:To study the effect of RFTVR and CO2 laser on the improvement of symptoms,QOL and vas of patients with early laryngeal cancer..Methods:In this study,120 patients with laryngeal cancer diagnosed and treated from January 2015 to December 2016 were taken as research objects.All patients were randomly divided into observation group and control group,60 patients in each group.Patients in observation group were treated with RFTVR,and patients in control group were treated with new-type fiber-optic CO2 laser.The patients in the two groups were treated with cisplatin injection.The differences of perioperative indexes,swallowing function,pronunciation function,survival period,QOL score and VAS score between the two groups were compared.Results:There was no significant difference in the amount of intraoperative bleeding,operation time and hospitalization time between the two groups(P>0.05);the correct swallowing of the observation group was significantly higher than that of the control group.After treatment,jitter,shimmer and HNR of the two groups were significantly improved,and jitter and shimmer of the observation group were significantly lower than that of the control group,and HNR was significantly higher than that of the control group(P<0.05)The QOL score and VAS score of the two groups were significantly improved,and the QOL score of the observation group was significantly higher than that of the control group and the VAS score was significantly lower than that of the control group(P<0.05);the total survival period and tumor free survival period of the observation group were significantly higher than that of the control group.Conclusion:Compared with CO2 laser treatment,the swallowing function and voice function of patients treated by low temperature plasma radiofrequency ablation were significantly improved,and the life quality of patients was significantly improved by prolonging the survival period of patients.

关 键 词：CO2激光治疗 低温等离子射频消融手术 喉癌 发音功能 吞咽功能 

分 类 号：R739.65[医药卫生—肿瘤]