黄芪多糖对繁殖猕猴生长性能、血液生理生化指标及腹泻发病率的影响  

Effects of Astragalus Polysaccharides on Growth Performance,Blood Physiological and Biochemical Indexes and Incidence of Diarrhea in Breeding Rhesus Monkeys

作　　者：陈丽雄[1] 王俊斌[1] 李艳艳[1] 徐鸿界 禹文海[1] 马进[1] 杨凤梅[1] 段素琴[1] 杨亚平 刘权 和占龙[1] 赵远[1] CHEN Lixiong;WANG Junbin;LI Yanyan;XU Hongjie;YU wenhai;MA Jin;YANG Fengmei;DUAN Suqin;YANG Yaping;LIU Quan;HE Zhanlong;ZHAO Yuan(Institute of Medical Biology,Chinese Academy of Medical Sciences,Kunming 650118,China)

机构地区：[1]中国医学科学院医学生物学研究所

出　　处：《实验动物科学》2019年第6期44-49,共6页Laboratory Animal Science

基　　金：中国医学科学院协同创新项目(2016-I2M-2-001,2018-I2M-3-002);昆明市科技创新和服务能力提升计划重点项目(2016-2-R-07674);云南省重大科技专项(2017ZF020);云南省科技创新人才计划(2015HC027)

摘　　要：目的通过饲喂黄芪多糖对繁殖猕猴生长性能、血液生理生化及腹泻发病率的影响,研究黄芪多糖在实验动物饲养管理中的应用。方法选取不同年龄阶段的繁殖猕猴60只在饲料中添加0.1%的黄芪多糖,每日饲喂一次。实验前、实验1月后、实验3月后分别采血测生理和生化指标、称体质量、统计腹泻发病率。结果随着黄芪多糖添加时间的延长,体质量都成上升的趋势,血常规中白细胞、淋巴细胞数也呈上升趋势。血液生化中谷草转氨酶、谷丙转氨酶、总胆红素、尿素、总胆固醇、甘油三酯、高密度脂蛋白胆固醇、低密度脂蛋白胆固醇、镁、C3、C4、Ig A、Ig G都呈上升趋势,血糖呈下降趋势;随着黄芪多糖添加时间的延长,繁殖猕猴腹泻的数量也呈下降的趋势。结论黄芪多糖能明显提高繁殖猕猴的饲料利用率、有效调节免疫力、对繁殖猕猴的腹泻也有很好的预防和治疗作用。Objective To study the effect of Astragalus Polysaccharides on the growth performance,blood physiology,biochemistry and diarrhea incidence of breeding macaque.Method Sixty breeding macaques of different ages were fed with Astragalus Polysaccharides once a day.Before the experiment,1 month after the experiment and 3 months after the experiment,the physiological and biochemical indexes,body weight and incidence of diarrhea were measured.Result With the increase of Astragalus polysaccharides,the body weight and the number of white blood cells and lymphocytes in blood routine were increased.In blood biochemistry,glutamic oxaloacetylase,glutamic pyruvic transaminase,total bilirubin,urea,total cholesterol,triglyceride,highdensity lipoprotein cholesterol,low-density lipoprotein cholesterol,magnesium,C3,C4,Ig A and IgG all showed an upward trend,while blood glucose showed a downward trend.With the increase of Astragalus polysaccharide,the number of diarrhea in breeding macaque also decreased.Conclusion Astragalus polysaccharide can obviously improve the feed utilization rate of breeding macaque,effectively regulate immunity,and also has a good prevention and treatment effect on diarrhea of breeding macaque.

关 键 词：黄芪多糖 繁殖猕猴 影响 

分 类 号：R-332[医药卫生]