缺血性卒中患者抗血小板药物依从性现状调查及影响因素  

Status and influencing factors of antiplatelet drug compliance in patients with ischemic stroke

作　　者：岳赞[1] 王惠娟[1] 王炳雷[1] 边鑫[1] 李艳[1] 沈建华[1] Yue Zan;Wang Huijuan;Wang Binglei;Bian Xin;Li Yan;Shen Jianhua(Department of Neurology,the Second Hospital of Hebei Medical University,Shijiazhuang 050000,China)

机构地区：[1]河北医科大学第二医院神经内科,河北石家庄050000

出　　处：《临床荟萃》2020年第3期233-237,共5页Clinical Focus

摘　　要：目的调查缺血性脑卒中患者抗血小板药物依从性现状及其影响因素。方法选取于我院神经内科住院的急性脑梗死患者739例,记录其一般资料及相关危险因素,随访其出院3个月、6个月、1年时抗血小板药物的服用情况、停药原因。结果出院3个月、6个月、1年时,服用抗血小板药物的患者例数与占比分别为677(91.61%),635(85.93%),608(82.28%)。高血压为服用抗血小板药物依从性的影响因素(OR=1.787,95%CI=1.133,2.817,P<0.05),好转自行停药(20.61%)为依从性差的主要原因。结论缺血性脑卒中患者抗血小板用药依从性随出院时间延长呈逐渐下降趋势。合并高血压患者的抗血小板药物依从性更佳。好转自行停药为依从性差的主要原因。Objective To investigate the status and influencing factors of antiplatelet drug compliancein patients with ischemic stroke.Methods A total of 739 patients with ischemic stroke were consecutively selected.The general clinical data and related risk factors of those patients were recorded,then they were followed up at three,six and twelve months after discharge in order to see the conditions of drug usageand the reasons of withdrawal(or dose reduction)of antiplatelet drug.Results The number and proportion of patients taking antiplatelet drugs at thee,six and twelve months were 677(91.61%),635(85.93%)and 608(82.28%),respectively.Hypertension was the independent factor associated with antiplatelet drug compliance(OR=1.787,95%CI=1.133,2.817,P<0.05).And the withdrawal after the improvement of disease on one’s own(20.61%)was the main reason for poor compliance.Conclusion Antiplatelet medication compliance in patients with ischemic stroke decreases gradually as discharge timegoes on.Patients with hypertension have better compliance with antiplatelet drugs.The main reason for poor complianceis that patients stopped taking drugs by themselves after getting better.

关 键 词：脑血管意外 血小板聚集抑制剂 病人依从 高血压 

分 类 号：R743[医药卫生—神经病学与精神病学]