养阴清热安神饮对减少原发性肾小球疾病激素治疗患者失眠发生率的临床观察  

Clinical Observation of Yangyin Qingre Anshen Decoction on Reducing Insomnia Incidence in Patients with Primary Glomerular Disease Treated with Hormone

作　　者：曾培鹃 王叙芬[1] ZENG Peijuan;WANG Xufen(Second Chinese Medicine Hospital,Yibin City,Sichuan Province,Yibin,Sichuan 644000,China)

机构地区：[1]四川省宜宾市第二中医医院,四川宜宾644000

出　　处：《大医生》2019年第18期98-99,共2页Doctor

基　　金：宜宾市重点科技项目(社会发展),(编号:2015SF041)。

摘　　要：目的观察养阴清热安神饮对减少原发性肾小球疾病激素治疗患者失眠发生率的临床观察。方法选取2016年1月至2019年5月经四川省宜宾市第二中医医院诊断为原发性肾小球疾病且同意使用激素治疗的84例患者,按照就诊顺序分为治疗组和对照组,各42例。对照组使用强的松治疗,治疗组在对照组基础上合用养阴清热安神饮加减治疗。比较两组治疗前后失眠症状的发生率以及尿蛋白、血浆白蛋白(ALB)、甘油三酯(TG)、胆固醇(CHO)水平。结果治疗组失眠发生率明显低于对照组(35.71%vs.61.90%,P<0.05)。与治疗前比较,治疗后两组患者的TG、CHO、24 h尿蛋白定量水平均明显下降,ALB水平明显升高(P<0.01);两组比较,差异无统计学意义(P>0.05)。结论养阴清热安神饮加减能减少原发性肾小球疾病激素治疗患者失眠发生率,提高患者生活质量。Objective To observe the clinical observation of Yangyin Qingre Anshen Decoction(YQAD)on reducing insomnia incidence in patients with primary glomerular disease treated with hormonotherapy.Methods From January 2016 to May 2019,A total of 84 patients diagnosed as primary glomerular disease by the Second Chinese Medicine Hospital of Yibin,Sichuan Province,who agreed to use hormonotherapy,were selected and divided into treatment group and control group according to the order of visit,with 42 patients in each group.The control group was treated with prednisone pine,the treatment group was treated with YQAD on the basis of control group.The incidence of insomnia and the levels of urine protein,plasma albumin(ALB),triglyceride(TG)and cholesterol(CHO)before and after treatment were compared between the two groups.Results The incidence of insomnia in the treatment group was significantly lower than that in the control group(35.71%vs.61.90%,P<0.05).Compared with before treatment,TG,CHO and 24 h urine protein quantitative levels in both groups were significantly decreased after treatment,and ALB levels were significantly increased(P<0.01).There was no significant difference in the above levels between the two groups after treatment(P>0.05).Conclusion YQAD can reduce the occurrence of insomnia and improve the quality of life for patients with primary glomerular disease treated with hormone.

关 键 词：养阴清热安神饮 激素 原发性肾小球疾病 失眠 

分 类 号：R73[医药卫生—肿瘤]