重复经颅磁刺激(rTMS)在创伤后应激障碍(PTSD)的应用进展  

Progress in Application of Repetitive Transcranial Magnetic Stimulation(rTMS)in Post-traumatic Stress Disorder(PTSD)

作　　者：孟祥虹 黄满丽[2] MENG Xianghong;HUANG Manli(Ningbo Psychiatric Hospital,Ningbo,Zhejiang 315032,China;Department of Mental Health,First Affiliated Hospital of School of Medicine,Zhejiang University,Zhejiang Key Laboratory of Diagnosis,Treatment and Prevention of Mental Disorders,Hangzhou 310009,China)

机构地区：[1]宁波市精神病院,浙江宁波315032 [2]浙江大学医学院附属第一医院精神卫生科、浙江省精神障碍诊疗和防治技术重点实验室,浙江杭州310009

出　　处：《大医生》2019年第17期149-150,166,共3页Doctor

摘　　要：创伤后应激障碍(PTSD)是一种创伤和压力相关的疾病,其特征在于创伤记忆侵入、躲避创伤相关刺激、认知小计改变、唤醒增强和行为过激的核心症状,可能导致严重的社会或职业功能障碍。PTSD对个体的生活、工作、家庭方面功能损害很大,有调查显示全世界超过70%的人都会经历创伤性事件,31%的人会经历4次以上,在中国52.5%的人会经历创伤性事件。其终身患病率为1.3%~12.2%。与PTSD相关的脑机制被追溯到与杏仁核、额叶和海马相关的特定途径。虽然药物和心理治疗已被证明有助于减轻症状,并治疗其共病焦虑或抑郁症状,但是仍有三分之一的患者症状并没有得到改善。Post-traumatic stress disorder(PTSD)is a trauma and stress-related disease characterized by traumatic memory invasion,avoidance of trauma-related stimuli,changes in cognitive subtotals,enhanced arousal and excessive behavior,which may lead to serious social or occupational dysfunction.PTSD has great impairment on individual's life,work and family functions.Surveys show that more than 70%of people in the world will experience traumatic events,31%will experience more than four times.In China,52.5%will experience traumatic events.The lifetime prevalence was 1.3%~12.2%.Brain mechanisms associated with PTSD have been traced back to specific pathways related to amygdala,frontal lobe and hippocampus.Although medication and psychotherapy have been shown to help alleviate symptoms and treat comorbid anxiety or depression symptoms,one third of patients still have symptoms that have not improved.

关 键 词：经颅磁刺激 无创 无痛 神经刺激技术 

分 类 号：R74[医药卫生—神经病学与精神病学]