病理在克罗恩病诊断中的价值  

Value of pathology in diagnosis of Crohn′s disease

作　　者：肖书渊 叶子茵[2] Xiao Shuyuan;Ye Ziyin(Department of Pathology,Zhongnan Hospital,Center for Pathology and Molecular Diagnostics,Wuhan University,Wuhan 430071,China;Department of Pathology,The First Affiliated Hospital,Sun Yat sen University,Guangzhou 510080,China)

机构地区：[1]武汉大学中南医院病理科,武汉大学病理中心430071 [2]中山大学附属第一医院病理科,广州510080

出　　处：《中华炎性肠病杂志（中英文）》2020年第1期7-11,共5页Chinese Journal of Inflammatory Bowel Diseases

摘　　要：克罗恩病的病理形态表现多样,且多不具备诊断特异性,活检标本病理诊断常常难度较大。肠镜系统性多部位活检,是克罗恩病病理诊断的重要基础。掌握克罗恩病病理的基本核心与组织学特征全貌,可为诊断提供重要的信息。本文通过介绍克罗恩病活检中具有诊断价值的组织学特征、早期克罗恩病的组织学特征、克罗恩病与肠结核、肠白塞病、肠血管病及淋巴瘤等的鉴别诊断,阐明病理在克罗恩病诊断中的价值。Histopathologic changes of Crohn′s disease vary among patients.Individual morphologic features are usually non specific,particularly in a single biopsy or from a single site.Systemic multiple biopsies and understanding of the core histopathologic features are vital to correct pathological diagnosis of Crohn′s disease.In this article,we review diagnostic histopathologic features of Crohn′s disease and changes in early stage Crohn′s disease,and discuss key differential features between Crohn′s disease and intestinal tuberculosis,intestinal Behcet′s disease,intestinal vascular disorder,and lymphoma,to emphasize the importance of pathology in the multidisciplinary diagnosis of Crohn′s disease.

关 键 词：克罗恩病 肠结核 肠白塞病 肠血管病 淋巴瘤 病理 

分 类 号：R57[医药卫生—消化系统]