372例住院活动期溃疡性结肠炎患者的营养风险筛查  

Nutritional risk screening in 372 patients with active ulcerative colitis during hospitalization

作　　者：王凤纤 缪应雷[2] 张晖敏[1] 唐源[1] 李红纳 Wang Fengxian;Miu Yinglei;Zhang Huimin;Tang Yuan;Li Hongna(Department of Gastroenterology,The First People′s Hospital of Qujing City,Qujing 655000,Yunnan Province,China;Department of Gastroenterology,The First Affiliated Hospital,Kunming Medical University,Kunming 650032,China)

机构地区：[1]云南省曲靖市第一人民医院消化内科,655000 [2]昆明医科大学第一附属医院消化内科,650032

出　　处：《中华炎性肠病杂志（中英文）》2020年第1期47-50,共4页Chinese Journal of Inflammatory Bowel Diseases

基　　金：国家自然科学基金(81670501、81660100)。

摘　　要：目的探讨住院的活动期溃疡性结肠炎(UC)患者的营养风险状况。方法回顾性纳入2013年1月至2017年6月在曲靖市第一人民医院、昆明医科大学第一附属医院住院的372例活动期UC患者为研究对象,收集患者的临床资料,包括营养风险筛查2002(NRS2002)评分。根据NRS2002评分结果,把研究对象分为有和无营养风险两组,对比两组患者的临床特征,并进行营养风险的单因素和多因素分析。结果244例(65.6%)住院的活动期UC患者存在营养风险。与无营养风险组患者相比,有营养风险组患者的体质指数(BMI)[(16.76±2.41)kg/m^2比(21.93±2.34)kg/m^2,P<0.001)]更低;Mayo评分更高(9.90±2.07比6.89±2.81,P<0.001);重度患者(65.6%比18.0%,P<0.001)、广泛结肠型患者(50.0%比33.6%,P<0.001)和慢性复发型患者比例更高(91.4%比78.9%,P<0.001);血红蛋白(HGB)水平[(118.05±24.85)g/L比(139.09±18.26)g/L,P<0.001)]和白蛋白水平[(34.25±6.70)g/L比(38.81±4.57)g/L],P<0.001)]更低。多因素分析显示低Mayo评分是营养风险的保护因素,低BMI、低HGB、慢性复发型、重度活动、广泛结肠型是营养风险的危险因素。结论UC患者营养风险的发生率高,具有营养风险的患者病情更重、疾病范围更广、慢性复发的比例更高。Objective To investigate the nutritional risk status of hospitalized patients with active ulcerative colitis(UC).Methods Three hundred and seventy two active UC patients who were admitted to The First People′s Hospital of Qujing City and The First Affiliated Hospital of Kunming Medical University from January 2013 to June 2017 were retrospectively included as the research objects,and clinical data of the patients were collected,including nutrition risk screening 2002(NRS2002)score.Based on the results of NRS 2002 score,patients were divided into two groups:nutritional risk group and non nutritional risk group.Clinical characteristics of these two groups were compared,and univariate and multivariate analyses of nutritional risk were performed.Results Two hundred and fourty four(65.6%)hospitalized active UC patients were at nutritional risk.Compared to non nutritional risk group,nutritional risk group had lower BMI[(16.76±2.41)kg/m^2 vs.(21.93±2.34)kg/m^2,P<0.001],higher Mayo score(9.90±2.07 vs.6.89±2.81,P<0.001),higher ratio of severe patients(65.6%vs.18.0%,P<0.001),higher ratio of patients with whole colonic type(50.0%vs.33.6%,P<0.001),higher ratio of chronic relapsed patients(91.4%vs.78.9%,P<0.001),lower hemoglobin level[(118.05±24.85)g/L vs.(139.09±18.26)g/L,P<0.001]and lower albumin level[(34.25±6.70)g/L vs.(38.81±4.57)g/L,P<0.001].Multivariate analysis showed that the low Mayo score was a protective factor for nutritional risk,and low BMI,low hemoglobin,chronic relapsed,severe disease activity and whole chronic type were risk factors for nutritional risk.Conclusion The incidence of nutritional risk is high in hospitalized patients with active UC.Patients with nutritional risk have heavier illness,broader range of disease,and higher proportion of chronic relapse.

关 键 词：溃疡性结肠炎 营养风险 营养风险筛查2002 

分 类 号：R57[医药卫生—消化系统]