神经心理测试在阿尔茨海默病和额颞叶变性认知损害早期的应用基础  

Neuropsychological tests in cognitive impairment of Alzheimer’s disease and frontotemporal degeneration

作　　者：葛芳芳 李延峰[2] Ge Fang-fang;Li Yan-feng(Department of Neurology,Xi’an International Medical Center Hospital;Department of Neurology,Peking Union Medical College Hospital,CAMS&PUMC)

机构地区：[1]西安国际医学中心医院神经内科 [2]北京协和医院神经内科

出　　处：《阿尔茨海默病及相关病杂志》2020年第1期65-69,共5页Chinese Journal of Alzheimer's Disease and Related Disorders

摘　　要：早期临床检测阿尔茨海默病和额颞叶变性所存在的轻微认知损害,并提高其鉴别诊断价值至关重要。尽管受试者的症状诉求是最为早期的征象,但需要相对客观的检测手段进行评估,神经心理测试作为一种相对客观的工具,能检测认知损害,监测疾病进展,评估药物疗效,被广泛应用于临床研究,本文就其在阿尔茨海默病和额颞叶变性的应用基础以及价值进行综述。Clinical detection of mild cognitive impairment in Alzheimer’s disease and frontotemporal lobar degenerationin early stage is essential to improve the differential diagnosis.Although the subject’s complaint is the earliest sign,it requires relatively objective evidence.Neuropsychological testing,as a relatively objective tool,can detect cognitive impairment,monitor disease progression and evaluate treatmentefficacy.This paper reviews the application basis and clinicalvalue of neuropsychological testing in differential AD and FTLD.

关 键 词：阿尔茨海默病 额颞叶变性 神经心理测试 

分 类 号：R749.1[医药卫生—神经病学与精神病学]