“提示-目标”视觉实验范式分析枕叶梗死偏盲患者的视觉空间注意障碍研究  

Analysis of visual spatial attention disorder in hemianopia patients with occipital lobe infarction by"Tip-Target"visual experimental paradigm

作　　者：郑宗菊[1] Zheng Zongju(The Banan District People's hospital of Chongqing City,Chongqing 401320)

机构地区：[1]重庆市巴南区人民医院,重庆401320

出　　处：《基层医学论坛》2020年第7期912-914,共3页The Medical Forum

摘　　要：目的采用"提示-目标"视觉实验范式分析枕叶急性脑梗死偏盲患者的视觉空间注意障碍。方法以2016年1月—2019年1月我院收治的15例枕叶急性脑梗死偏盲患者为研究对象(观察组),另选择15例健康人作为对照(对照组)。用E-prime软件编写"提示-目标"视觉实验范式程序,包括Pop-out视觉搜索任务(反映被动内隐视觉空间注意)和"提示-目标"任务(反映主动内隐视觉空间注意),比较2组反应时(RT)、正确率和个体内反应时标准差(ISD),分析这三个指标与视野指数的关系。结果观察组左、右侧视野RT均明显高于对照组(P<0.05),观察组左、右侧视野正确率均明显低于对照组(P<0.05)。观察组左侧视野ISD明显高于对照组(P<0.05),2组右侧视野ISD比较无统计学差异(P>0.05)。无论提示是否有效,观察组RT和ISD均高于对照组,而正确率低于对照组(P<0.05)。视野指数与R T和ISD呈负相关,而与正确率呈正相关(P<0.05)。结论枕叶急性脑梗死偏盲患者无论是在完成主动或是被动内隐视觉空间注意时,其注意力均不稳定,波动性较大,注意力维持困难。Objective The visual spatial attention disorder of hemianopic patients with occipital lobe acute cerebral infarction was analyzed by the visual experiment paradigm of"prompt-target".Methods From January 2016 to January 2019,15 patients with hemianopia due to occipital lobe acute cerebral infarction were selected as the study group,and 15 healthy persons were selected as the control group.The visual experiment paradigm program of"prompt-target"was compiled with E-prime software,including Pop-out visual search task(reflecting passive implicit visual spatial attention)and"prompt-target"task(reflecting active implicit visual spatial attention).The response time(RT),accuracy and standard deviation of individual internal response time(ISD)were compared between the two groups.Pearson method was used to analyze the relationship between these three indexes and visual field index.Results The left and right visual field RT of the observation group was significantly higher than that of the control group(P<0.05),and the correct rate of left and right visual field of the observation group was significantly lower than that of the control group(P<0.05).The ISD of the left visual field in the observation group was significantly higher than that in the control group(P<0.05),but there was no significant difference between the two groups in the ISD of the right visual field(P>0.05).The RTand ISDofthe observation group were higher than those ofthe control group,and the correct rate was lower than that of the control group(P<0.05).Visual field index was negatively correlated with RT and ISD,but positivelycorrelated with accuracy(P<0.05).Conclusion The attention ofhemianopia patients with occipital lobe acute cerebral infarction is unstable,volatile and difficult tomaintainwhen theycomplete active or passive implicit visual spatial attention.

关 键 词：急性脑梗死 枕叶 偏盲 视觉空间注意障碍 “提示-目标”视觉实验范式 

分 类 号：R743.33[医药卫生—神经病学与精神病学] R77[医药卫生—临床医学]