高通量氙光传递窗与紫外传递窗灭菌效果观察  

Comparison of sterilization effect between High-throughput Xenon Ray Pass Box and ultraviolet Pass Box

作　　者：许琦 赵月 黄伟健 宋琳亮 康生 刘毅 和君 傅江南 XU Qi;ZHAO Yue;HUANG Weijian;SONG Linliang;KANG Sheng;LIU Yi;HE Jun;FU Jiangnan(Institute of Laboratory Animal Science,Jinan University,Guangzhou 510632,China.;Xi’an Fukang Air Purification Equipment and Engineering Co.Ltd.,Xi’An 710000)

机构地区：[1]暨南大学实验动物管理中心,广州510632 [2]西安富康空气净化设备工程有限公司,西安710000

出　　处：《中国比较医学杂志》2020年第3期44-49,共6页Chinese Journal of Comparative Medicine

基　　金：广东省自然科学基金面上项目(2019A1515011994);广东省科技计划项目(2016A030303013);广东卫生厅医学科研基金(A2018391)。

摘　　要：目的传递窗作为实验动物屏障设施内物品传递的通道,主要是通过紫外灯照射物品表面达到消毒目的。针对其照射时间长、使用频率高、影响因素复杂、且消毒效果不稳定等问题,本研究对比了紫外传递窗和高通量氙光传递窗在不同时间点的杀菌效果。方法比较分析两种传递窗在不同的时间点对5种标准菌株(金黄色葡萄球菌、绿脓杆菌、大肠杆菌、白色念珠菌、枯草芽孢杆菌)的杀菌效果。结果高通量氙光传递窗1 min杀菌率达99. 85%,5 min可达100%;紫外传递窗5 min达不到杀菌效果,对不同菌种灭菌效率差异大,照射30 min杀菌率方可达99. 91%。结论与传统的紫外传递窗相比,高通量氙光传递窗5 min即可达到杀菌效果,它有望替代紫外传递窗。Objective Pass-through box,also called pass-through chambers and pass-through windows,allow for the transfer of parts and equipment into and out of a barrier facility. The common use of pass-through box is to sterilize the materials under the exposure of UV radiation. The traditional UV lamps need long time exposure,but the effect is not stable. A xenon( Xe) arc lamp is a specialized type of gas-discharge lamp that produces light by passing electricity through ionized xenon gas at high pressure and emit radiant energy within the UV-C band. In this study,the bactericidal efficacy of ultraviolet pass box and high-throughput xenon ray pass box was compared at indicated time points. Methods After the exposure of the two types of devices at indicated time points respectively,the effects on the staphylococcus aureus,pseudomonas aeruginosa,escherichia coli,candida albicans and bacillus subtilis were tested. Results The efficiency of the xenon arc lamps was 99. 85% with 1-min exposure and 100% with 5-min exposure;The sterilization efficiency of traditional UV lamps below quality in 5 minutes,and the sterilization efficiency of different bacterias varied greatly. However,the sterilization efficiency is about 99. 91% after 30-min irradiation duration. Conclusions The efficiency of the xenon arc lamps can achieve bactericidal effect in 5 minutes,and could replace the UV lamps in the future.

关 键 词：传递窗 紫外灯 氙气灯 杀菌效果 5种标准菌株 

分 类 号：R-33[医药卫生]