PET/CT显像在化疗相关心肌损伤中的应用  

Application of PET/CT imaging in chemotherapy-related cardiotoxicity

作　　者：孟天宇 于江媛[1] 李囡[1] 杨志[1] Meng Tianyu;Yu Jiangyuan;Li Nan;Yang Zhi(Key Laboratory of Carcinogenesis and Translational Research(Ministry of Education/Beijing),Department of Nuclear Medicine,Peking University Cancer Hospital&Institute,Beijing 100142,China)

机构地区：[1]北京大学肿瘤医院暨北京市肿瘤防治研究所核医学科、恶性肿瘤发病机制及转化研究教育部重点实验室,100142

出　　处：《中华核医学与分子影像杂志》2020年第3期179-182,共4页Chinese Journal of Nuclear Medicine and Molecular Imaging

摘　　要：心肌损伤是肿瘤化疗常见的并发症,是肿瘤患者预后的影响因素之一。早期识别并干预化疗相关心肌损伤十分重要。目前常用的临床、影像学及实验室检查方法均存在不足之处,而PET/CT显像目前尚未广泛应用于化疗相关心肌损伤。该文就目前PET/CT显像在化疗相关心肌损伤动物实验及人体试验中的应用及不足进行综述。Chemotherapy-related cardiotoxicity is common and has become one of the factors that affect the prognosis of patients.Early identification and intervention of chemotherapy-related cardiotoxicity is very important.Currently,the commonly used clinical,imaging and laboratory examination methods have their own shortcomings,while PET/CT imaging has not been widely used for chemotherapy-related cardiotoxicity.This article reviews the current application and deficiencies of PET/CT imaging in animal experiments and human trials of chemotherapy-related cardiotoxicity.

关 键 词：心脏毒性 药物疗法 正电子发射断层显像术 体层摄影术 X线计算机 发展趋势 

分 类 号：R730[医药卫生—肿瘤]