不同种类交联剂对牙本质Ⅰ型胶原生物改性作用的研究进展  

Progress in biomodification of dentin typeⅠcollagen by different types of cross-linkers

作　　者：孔维婧 顾新华[1] 孙健[1] Kong Weijing;Gu Xinhua;Sun Jian(Department of Prosthodontics,The First Affiliated Hospital,Zhejiang University,School of Medicine,Hangzhou 310003,China)

机构地区：[1]浙江大学医学院附属第一医院口腔修复科,杭州310003

出　　处：《中华口腔医学杂志》2020年第2期135-138,共4页Chinese Journal of Stomatology

基　　金：浙江省自然科学基金(LY16H140001);浙江省医药卫生科技计划(2019KY383)。

摘　　要：建立稳定的树脂-牙本质混合层是提高修复体粘接耐久性的有效方法。交联剂对牙本质的生物改性可增强胶原的力学性能及抗酶解性,抑制脱矿进程并促进牙本质再矿化,具有预防龋齿以及改善粘接剂性能的临床价值。本文分类阐述不同交联剂对牙本质Ⅰ型胶原的生物改性作用。Establishing a stable resin-dentin hybrid layer is an effective method to improve the adhesion durability of the restoration.The biomodification of dentin by cross-linkers can enhance the mechanical properties of collagen and resistance to enzymatic hydrolysis while,inhibiting the process of demineralization and promoting the remineralization of dentin,which has the potential clinical applicability of preventing dental caries and improving adhesive property.This review summarizes the biomodification of dentin typeⅠcollagen by different cross-linkers.

关 键 词：牙本质 胶原Ⅰ型 牙本质粘结剂 交联剂 

分 类 号：R78[医药卫生—口腔医学]