关注胍类阳离子消毒剂对肺的损害  

Concern about lung damage caused by guanidine cationic disinfectants

作　　者：屈卫东[1] Qu Weidong(Key Laboratory of the Public Health Safety,Ministry of Education/Department of Environmental Health,School of Public Health,Fudan University,Shanghai 200032,China)

机构地区：[1]复旦大学教育部公共卫生安全教育部重点实验室复旦大学公共卫生学院环境卫生学教研室,上海200032

出　　处：《中华预防医学杂志》2020年第2期121-123,共3页Chinese Journal of Preventive Medicine

基　　金：国家自然科学基金重点项目(20163088)。

摘　　要：本文概述了胍类消毒剂在我国的使用情况和胍类阳离子消毒剂在韩国使用引发了肺纤维化等严重肺损伤事件。评述了我国学者利用超声雾化技术,模拟人类实际暴露场景染毒,证明了聚六亚甲基胍能引起肺纤维化。这些结果警示需充分重视胍类消毒剂引起的肺损伤问题,探究健康危害的机制,从而为保护公共卫生安全及其相应政策的制定提供重要科学依据。This article summarized the use of guanidine disinfectants in China and the use of guanidine cationic disinfectants,polyhexamethylene guanidine(PHMG),in South Korea,which had caused severe lung damage events such as pulmonary fibrosis.The authors reviewed the studies that Chinese scientists employed ultrasonic atomization technology to simulate the actual scenario of human exposure to PHMG and proved the findings that PHMG could cause pulmonary fibrosis.These results could highlight the necessity of full attention to lung damage caused by guanidine disinfectants and its mechanism,so as to provide the important scientific basis for the protection of public health safety and the formulation of corresponding policies.

关 键 词：胍类 肺损伤 消毒剂 

分 类 号：R[医药卫生]