Smoking history increases the risk of long-term mortality after thoracic endovascular aortic repair in patients with an uncomplicated type B dissection  

作　　者：Hui-Qiang Gao Chang-Wei Ren Sheng Yang Lian-Jun Huang Li-Zhong Sun Shang-Dong Xu 

机构地区：[1]Department of Cardiac Surgery,Beijing Anzhen Hospital,Beijing Institute of Heart,Lung&Vascular Diseases,Capital Medical University,Beijing 100029,China [2]Department of Intervention,Beijing Anzhen Hospital,Beijing Institute of Heart,Lung&Vascular Diseases,Capital Medical University,Beijing 100029,China

出　　处：《Chinese Medical Journal》2020年第4期402-407,共6页中华医学杂志（英文版）

基　　金：This work was supported by a grant from the National Natural Science Foundation of China(No.11972215).

摘　　要：Background:The preferred treatment for uncomplicated type B dissection(thoracic endovascular aortic repair[TEVAR]or medical)is still under debate.Since 2001,our center has performed TEVAR for uncomplicated type B dissection.Based on our data,5-and 10-year survival rates among patients with uncomplicated type B dissection after TEVAR were 96.5%and 83.0%,respectively.We,therefore,believe that TEVAR is preferable for uncomplicated type B dissections.This study analyzed the impact of a pre-operative smoking history on long-term survival after TEVAR in patients with uncomplicated type B dissections.Methods:From May 2001 to December 2013,data from 751 patients with type B dissections were collected and analyzed.Patients were divided into two groups(337 smoking patients and 414 non-smoking patients).The Kaplan-Meier method and log-rank test were used to compare survival curves of the two groups.Multivariable analyses using the Cox proportional hazards model were used to estimate the effects of smoking on survival rates.Results:The 5-and 10-year survival rates of non-smokers were 97.6%(95%confidence interval[CI],96.0%-99.2%)and 87.0%(95%CI,81.6%-92.7%),respectively,and 94.9%(95%CI,92.2%-97.7%)and 73.8%(95%CI,62.3%-87.5%)for smokers,respectively(Log-rank test,P=0.006).Multivariable analyses showed that smoking increased the risk of death during follow-up,2.1-fold when compared to non-smokers(P=0.039).Conclusion:A pre-operative smoking history increases long-term mortality rates after TEVAR in patients with uncomplicated type B dissections.

关 键 词：SMOKING TEVAR UNCOMPLICATED TYPE B DISSECTION Survival rate 

分 类 号：R655[医药卫生—外科学]