冰冻切片识别早期肺腺癌准确性的研究进展  

Advances in the accuracy of the frozen section(FS)identification for early-stage lung adenocarcinoma

作　　者：王潇梵 陈东来[2] 朱尔家 陈昶[2] 张永胜[3] 陈勇兵[1] Wang Xiaofan;Chen Donglai;Zhu Erjia;Chen Chang;Zhang Yongsheng;Chen Yongbing(Department of Thoracic Surgery,the Second Affiliated Hospital of Soochow University,Medical College of Soochow University,Suzhou 215001,China;Department of Thoracic Surgery,Shanghai Pulmonary Hospital,Tongji University School of Medicine,Shanghai 200433,China;Department of Pathology,the Second Affiliated Hospital of Soochow University,Medical College of Soochow University,Suzhou 215001,China)

机构地区：[1]苏州大学附属第二医院胸心外科,苏州215001 [2]同济大学附属上海市肺科医院胸外科,200433 [3]苏州大学附属第二医院病理科,苏州215001

出　　处：《中华胸心血管外科杂志》2020年第2期125-128,共4页Chinese Journal of Thoracic and Cardiovascular Surgery

基　　金：苏州市科技发展(民生科技)项目(SS2019061);苏州市重点学科项目(SZXK201803);苏州市胸部肿瘤重点实验室项目(SZS201907)。

摘　　要：冰冻切片技术现已广泛用于各种临床外科手术,其报告速度明显优于传统石蜡切片,在指导手术切除范围及初步病理诊断中有重要意义,但现阶段对冰冻切片识别早期肺腺癌的准确性仍有争议。本文旨在总结冰冻切片对早期肺腺癌识别的准确性,分析其干扰因素,对比冰冻切片与最终石蜡切片的结果异同,探讨冰冻切片能否对外科手术切除早期肺腺癌起到准确的提示和指导作用。The frozen section(FS)technology has been widely used in the process of surgical pathology since its time-saving nature exhibited superiority over traditional paraffin method.Therefore FS,of great value in providing preliminary pathological diagnosis,offers guidance in the extension of surgical resection.However,it remains controversial whether the early-stage lung adenocarcinoma could be accurately identified in FS.This review aims to generalize the studies concerning the accuracy of FS in identifying early-stage lung adenocarcinoma,analyzing the interference factors,comparing the similarities and differences between frozen sections and traditional paraffin sections.It also gives insight into whether FS can provide significant guidance for surgeons to perform resection on early-stage lung adenocarcinoma.

关 键 词：手术切除范围 临床外科手术 冰冻切片技术 早期肺腺癌 病理诊断 石蜡切片 干扰因素 外科手术切除 

分 类 号：R734.2[医药卫生—肿瘤]