牙周支持治疗对牙周炎患者种植体脱落和种植体周围炎影响的Meta分析和系统评价  

Meta Analysis and Systematic Evaluation of the Effect of Supportive Periodontal Therapies on Implant Loss and Peri-implantitis in Patients with Periodontitis

作　　者：张芷玮 黄姣[1] ZHANG Zhiwei;HUANG Jiao(College of Stomatology,Chongqing Medical University,Chongqing 401147,China)

机构地区：[1]重庆医科大学附属口腔医院,重庆401147

出　　处：《中国医学创新》2020年第6期145-151,共7页Medical Innovation of China

基　　金：2016年重庆市高校创新团队建设计划资助项目(CXTDG201602006);重庆市高校市级口腔生物医学工程重点实验室资助项目(渝教科[2014]55号)。

摘　　要：目的:系统评价规律的牙周支持治疗(supportive periodontal therapies,SPT)对牙周炎患者种植修复的长期疗效。方法:计算机检索PubMed、Cochrane library、Embase、中国知网、万方数据库,联合手工检索,查找牙周炎患者行种植修复后,进行规律SPT的相关文献,检索时间为2000年1月-2018年10月。两位研究者独立完成文献筛选、资料提取。RevMan 5.3进行Meta分析。结果:最终纳入8篇文献。与牙周健康组相比,在SPT条件下,有牙周炎病史患者的种植体周围骨吸收[MD=0.33,95%CI(0.16,0.50),P=0.000 1]、种植体探诊深度[SMD=0.46,95% CI(0.14,0.78),P=0.005]均高于牙周健康组,种植体周围炎发生率高于健康牙周组;但是种植体脱落率差异无统计学意义(P>0.05)。结论:牙周炎患者经过牙周治疗后的种植修复后进行SPT,种植体远期存留率高。同时应注意,有牙周炎的种植患者具有更高的种植体周围骨吸收和发生种植体周围炎的风险。提示在临床工作中行种植治疗前积极治疗牙周炎,同时重视SPT对种植体存留和健康的重要性。Objective:To systematically evaluate the long-term effect of regular periodontal supportive therapy (SPT) on periodontitis patients.Method:PubMed,Cochrane Library,EMBASE,CNKI,Wanfang database were searched by computer,combined with manual search,to find the relevant literature of regular SPT for periodontitis patients after implant repair.The retrieval time was from January 2000 to October 2018.Two researchers independently completed literature screening and data extraction.Revman 5.3 for meta analysis.Result:Finally,8 articles were included.Compared with the periodontal health group,under SPT condition,the bone resorption around implant [MD=0.33,95% CI (0.16,0.50),P=0.000 1] and the implant probing depth [SMD=0.46,95% CI (0.14,0.78),P=0.005] in patients with periodontitis were higher than those in the healthy periodontal group,the incidence of peri-implantitis was higher than that of healthy periodontal group;however,there was no significant difference in implant loss rate (P>0.05).Conclusion:The long-term survival rate of implant is high when SPT is used in periodontitis patients after periodontal treatment.It should also be noted that patients with periodontitis have a higher risk of bone resorption around implant and peri-implantitis.It is suggested that periodontitis should be treated before implant treatment,and the importance of SPT for implant survival and health should be emphasized.

关 键 词：牙周炎 牙周支持治疗 种植体脱落 种植体周围炎 种植体周围骨吸收 META分析 

分 类 号：R781.42[医药卫生—口腔医学]