阴道放置卡前列甲酯栓与米索前列醇宫颈预处理对宫腔镜子宫黏膜下肌瘤电切术患者宫颈扩张和手术的影响  

Influence on Cervical Dilation and Operation of Cervical Pretreatment with Vaginal Placement of Carboprost Methylate Suppositorites and Misoprostol in Hysteroscopic Electrotomy for Submucous Uterine Myoma

作　　者：付海霞 FU Haixia(Jiamusi Maternal and Child Health Care,Jiamusi 154002,China)

机构地区：[1]黑龙江省佳木斯市妇幼保健院,黑龙江佳木斯154002

出　　处：《中国医学创新》2020年第2期137-140,共4页Medical Innovation of China

摘　　要：目的:对比宫腔镜子宫黏膜下肌瘤电切手术前两种宫颈预处理方式对患者宫颈扩张和手术的影响。方法:采用分层抽样法抽选80例子宫黏膜下肌瘤患者纳入本研究,均于2014年3月-2019年3月接受宫腔镜子宫黏膜下肌瘤电切术治疗,采用随机数字表法将其分为参照组(n=40)和研究组(n=40)。在宫腔镜子宫黏膜下肌瘤电切术治疗前,参照组实施阴道放置米索前列醇宫颈预处理,研究组实施阴道放置卡前列甲酯栓宫颈预处理。统计并比较两种术前预处理方式下宫颈扩张效果、围手术期相关指标情况以及药物不良反应和术后并发症发生情况。结果:研究组宫颈扩张宽度平均为(7.71±1.02)mm,大于参照组的(6.19±0.92)mm,差异有统计学意义(P<0.05);研究组宫颈扩张总有效率为97.50%,高于参照组的80.00%,差异有统计学意义(P<0.05);研究组手术时间、术后首次排气时间、住院时间均短于参照组,术中出血量少于参照组,差异均有统计学意义(P<0.05);研究组不良反应发生率为7.50%,参照组为5.00%,两组比较差异无统计学意义(P>0.05);研究组术后并发症发生率为2.50%,低于参照组的22.50%,差异有统计学意义(P<0.05)。结论:在宫腔镜子宫黏膜下肌瘤电切术前,对子宫黏膜下肌瘤患者实施阴道放置卡前列甲酯栓宫颈预处理,可以较好地扩张宫颈宽度,缩短手术时间,减少术中出血量和术后并发症,利于患者术后快速恢复,并且不会增加药物不良反应,临床应用价值较高。Objective: To study the influence on cervical dilation and operation of two cervical pretreatment modes in hysteroscopic electrotomy for submucous uterine myoma. Method: Through the stratified sampling method, 80 submucous uterine myoma patients underwent the hysteroscopic electrotomy from March 2014 to March 2019 were selected and randomly assigned to the reference group(n=40) and the study group(n=40). Before hysteroscopic submucosal myoma resection, the reference group performed cervical preconditioning with vaginal placement of Misoprostol, and the study group performed cervical preconditioning with vaginal placement of Carboprost Methylate Suppositorites. The cervical dilation effects, perioperative indicators, adverse drug reactions and postoperative complications of two groups were counted and compared. Result: The average cervical dilation width in the study group was(7.71±1.02) mm, more than(6.19±0.92) mm of the reference group, the difference was statistically significant(P<0.05). The overall effective dilation rate in the study group was 97.50%, higher than 80.00% of reference group, the difference was statistically significant(P<0.05). The operation time, initial exhaust time and hospitalization time in the study group were shorter than those of the reference group, while the intraoperative blood loss was less than that of the reference group, the differences were statistically significant(P<0.05). The adverse event rate in the study group was 7.50%, the reference group was 5.00%, there was no statistical significance between two groups(P>0.05). The postoperative complication rate in the study group was 2.50%, lower than 22.50% of the reference group, the difference was statistically significant(P<0.05). Conclusion: Before the hysteroscopic electrotomy for submucous uterine myoma, the cervical pretreatment with Carboprost Methylate Suppositorites can expand the cervical dilation width, shorten the operation time, reduce the intraoperative blood loss and postoperative complications, promote the fast

关 键 词：卡前列甲酯栓 米索前列醇 宫颈预处理 宫腔镜子宫黏膜下肌瘤电切术 宫颈扩张 

分 类 号：R737.33[医药卫生—肿瘤]