美沙拉嗪栓与柳氮磺吡啶栓治疗溃疡性结肠炎的对比研究  

Comparative Study of Mesalazine Suppository and Sulfasalazine Suppository in the Treatment of Ulcerative Colitis

作　　者：徐访访 孙彦胜 Fangfang Xu;Yansheng Sun(Jiangsu Xinyi Hospital,Xinyi,Jiangsu,221400,China)

机构地区：[1]江苏省新沂市中医院,江苏新沂221400

出　　处：《实用医学研究》2019年第2期63-64,共2页Practical medical research

摘　　要：对溃疡性结肠炎患者分别采用美沙拉嗪栓以及柳氮磺吡啶栓治疗分析比较临床治疗效果以及不良反应发生情况。选取我院溃疡性结肠炎患者150例,随机分成两组,实验组使用美沙拉嗪栓,对照组使用柳氮磺吡啶栓。根据临床症状、电子结肠镜复查结果进行对照。结果显示,总有效率对比治疗组达93.3%,对照组72.0%(P<0.05);不良反应发生率对比治疗组5.3%,对照组20.0%(P<0.05);复发率对比治疗组12.3%,对照组11.9%,差异无统计学意义。由此得出,用美沙拉嗪栓治疗溃疡性结肠炎效果好,不良反应少,值得临床推广。Mesalazine suppository and sulfasalazine suppository are used to treat patients with ulcerative colitis.The clinical efficacy and adverse reactions are compared.150 patients with ulcerative colitis in our hospital are randomly divided into two groups.The experimental group is treated with mesalazine suppository and the control group is treated with sulfasalazine suppository.The results of clinical symptoms and electronic colonoscopy are compared.The results show that the total effective rate was 93.3%in the control group and 72.0%in the control group(P<0.05);the incidence of adverse reactions is 5.3%in the control group and 20.0%in the control group(P<0.05);the recurrence rate is 12.3%in the control group and 11.9%in the control group,with no statistical significance.It is concluded that mesalazine suppository is effective in the treatment of ulcerative colitis with less adverse reactions,which is worthy of clinical promotion.

关 键 词：溃疡性结肠炎 美沙拉嗪栓 柳氮磺吡啶栓 

分 类 号：R57[医药卫生—消化系统]