大气压条件下离子分子反应装置的研制  

Development of Ion-molecular Reaction Device Under Atmospheric Pressure

作　　者：张立[1] 张菁[1] 郭寅龙[1] ZHANG Li;ZHANG Jing;GUO Yin-long(National Center for Organic Mass Spectrometry in Shanghai,Shanghai Institute of Organic Chemistry,Chinese Academy of Sciences,Shanghai 200032,China)

机构地区：[1]中国科学院,上海有机化学研究所,上海有机质谱中心,上海200032

出　　处：《分析测试技术与仪器》2020年第1期3-10,共8页Analysis and Testing Technology and Instruments

基　　金：中国科学院仪器设备功能开发技术创新项目(YG2010056)。

摘　　要：研制了一种大气压条件下离子分子的反应装置.装置的设计及性能与质谱特有的高灵敏度和高特异性相匹配,可以在大气压条件下进行离子产生并进行中性反应分子的引入,从而拓展离子分子反应的分子类型.装置可以精确控制离子分子反应时间,同时可以实现有机反应过程在线研究并可与液相色谱联用,从而可以为一些反应活泼中间体的结构和活性判断奠定试验基础.装置拓展了仪器的使用功能,应用范围得到提升,为有机反应研究工作者提供更全面的有机反应活性中间体分析.An atmospheric pressure ion-molecular reaction device has been developed.The design and performance of the device match the high sensitivity and specificity of the mass spectrometer(MS).The molecular types of ion-molecule reaction are expanded through the generation of ions and the introduction of neutral reactive molecules under atmospheric pressure.The ion molecule reaction time can be precisely controlled.At the same time,the organic reaction process can be realized online and can be combined with liquid chromatography,which is important for the comprehension of structure and activity judgment of some active reaction intermediates,thus,expands of the functions of the instrument and promotes its application scope,and a more comprehensive analysis for the active reaction intermediates can be provided for organic reaction researchers.

关 键 词：质谱 离子分子反应装置 中间体 反应机理 

分 类 号：O657.63[理学—分析化学]