The First Case of Human Herpesvirus 7-Related Epilepsy in the Republic of Belarus  

作　　者：Katerina Divakova Elena Kishkurno Tamara Amvrosieva Oxana Romanova Svetlana Belaya Igor Zaitsau Yuliya Shilova 

机构地区：[1]Pediatric Infectious Diseases Department,Belarusian State Medical University,Minsk 220116,Republic of Belarus [2]Republican Research and Practical Center for Epidemiology and Microbiology,Minsk 220114,Republic of Belarus [3]Infectious Diseases Department,Belarusian Medical Academy of Post-Graduate Education,Minsk 220013,Republic of Belarus [4]Republican Research and Clinical Center of Neurology and Neurosurgery,Minsk 220114,Republic of Belarus

出　　处：《Journal of Pharmacy and Pharmacology》2020年第3期73-76,共4页药剂与药理学（英文版）

摘　　要：Background:Human herpesvirus(HHV)-7 is usually associated with febrile seizures.Later onset and higher frequency of seizures are characteristic of pediatric HHV-7,compared with HHV-6 infection.The HHV-7-related severe neurological disorders are predominantly observed in immunocompromised individuals.Reports of healthy individuals with HHV-7 infection and diverse neurological disorders are limited.Patient Description:We present a case of HHV-7-related epilepsy in an immunocompetent 11-year old boy and extensive infectious and autoimmune testing positive only for HHV-7 in the cerebrospinal fluid.The patient made a good recovery after treatment with intravenous immunoglobulin and methylprednisolone.Discussion:This is the first reported case of epilepsy associated with HHV-7 in a previously healthy individual.It also demonstrates that intravenous immunoglobulin and steroids may be used in the course of this disorder and may be beneficial for recovery.

关 键 词：HHV-7 EPILEPSY CHILD CASE REPORT treatment 

分 类 号：R37[医药卫生—病原生物学]