幽门螺旋杆菌感染与大肠息肉的相关性  

Relationship between Helicobacter pylori infection and colorectal polyps

作　　者：潘程宇 滑永志[1] PAN Chengyu;HUA Yongzhi(Department of Gastroenterology,Affiliated Hospital of Intergrated Traditional Chinese and Western Medicine Nanjing University of Chinese Medicine,Nanjing 210028,China)

机构地区：[1]南京中医药大学附属中西医结合医院消化科,南京210028

出　　处：《临床与病理杂志》2020年第3期616-619,共4页Journal of Clinical and Pathological Research

基　　金：江苏省中医药局项目(JD201520)。

摘　　要：目的:探讨幽门螺旋杆菌感染与大肠息肉发生的相关性。方法:选择南京中医药大学附属中西医结合医院消化科2017年1月至2018年12月期间同时进行电子肠镜及幽门螺旋杆菌检查的住院患者共341例,分为肠息肉组及对照组,比较两组一般资料、幽门螺旋杆菌感染率及大肠息肉的个数、位置、大小、性质等。结果:肠息肉组幽门螺旋杆菌感染阳性率为59.1%,对照组幽门螺旋杆菌感染阳性率22.4%,差异有统计学意义(P<0.05)。肠息肉组中,大肠单发息肉患者幽门螺旋杆菌感染阳性率51.4%,多发息肉幽门螺旋杆菌感染阳性率69.8%,差异具有统计学意义(P<0.05)。幽门螺旋杆菌感染与患者年龄、性别及大肠息肉的位置、大小、性质无明显相关性(P>0.05)。结论:幽门螺旋杆菌感染可增加大肠息肉尤其是多发性大肠息肉的发病风险。Objective:To investigate the correlation between Helicobacter pylori infection and colorectal polyps.Methods:A total of 341 in-patients who underwent electronic enteroscopy and Helicobacter pylori examination at the same time from January 2017 to December 2018 in the Department of Gastroenterology of Affiliated Hospital of Intergrated Traditional Chinese and Western Medicine Nanjing University of Chinese Medicine were divided into two groups:the colorectal polyps group and the control group.The general data,Helicobacter pylori infection rate and the number,location,size and nature of large colorectal polyps of the two groups were analyzed.Results:The positive rate of Helicobacter pylori infection in colorectal polyps group was 59.1%,and that in control group was 22.4%.The difference was significant(P<0.05).In the colorectal polyp group,the positive rate of Helicobacter pylori infection was 51.4%in patients with single polyp and 69.8%in patients with multiple polyp(P<0.05).There was no significant correlation between Helicobacter pylori infection and age,sex,location,size and nature of colorectal polyps(P>0.05).Conclusion:Helicobacter pylori infection can increase the risk of colorectal polyps,especially multiple colorectal polyps.

关 键 词：幽门螺旋杆菌 大肠息肉 相关性 

分 类 号：R573[医药卫生—消化系统]