三维斑点追踪技术评价睡眠呼吸暂停综合征患者心脏功能  

Cardiac function in patients with sleep apnea syndrome was assessed using three-dimensional speckle tracking imaging technology

作　　者：周广琴 黄磊[1] 董珊珊[1] 秦文娟[1] 闫晓君[1] 田凤[2] 芦桂林[1] ZHOU Guang-qin;HUANG Lei;DONG Shan-shan(Ultrasound Diagnosis Department,the First Affiliated Hospital of Medical College of Shihezi University,Shihezi 832008,China;Department of neurology,the First Affiliated Hospital of Medical College of Shihezi University,Shihezi 832008,China)

机构地区：[1]石河子大学医学院第一附属医院超声诊断科,新疆石河子8320082 [2]石河子大学医学院第一附属医院神经内科,新疆石河子832008

出　　处：《吉林医学》2020年第4期801-805,共5页Jilin Medical Journal

基　　金：石河子大学医学院第一附属医院院级课题[项目编号:ZD201703]。

摘　　要：目的:应用三维斑点追踪成像技术(3D-STI)评价左心室收缩功能正常的阻塞性睡眠呼吸暂停综合征(OSAS)患者的心脏功能,并探讨其右心室应变与睡眠呼吸暂停程度的关系。方法:选择临床诊断为OSAS的患者60例,按照呼吸暂停低通气指数(AHI)分为:轻度组、中度组、重度组,每组各20例,另选20例健康人为阴性对照组;应用常规超声及3D-STI测量各组的右室功能指标,并比较各组间参数的差异性。结果:OSAS患者的整体纵向应变(GLS)、圆周应变(GCS)、径向应变(GRS)与正常对照组相比较,其数值明显减小,差异有统计学意义(P<0.05);重度OSAS组与轻、中度OSAS组相比较,GLS、GCS、GRS、右心室Tei指数、三尖瓣环收缩期峰值位移(TAPSE)均差异有统计学意义(P<0.05);中度OSAS患者的GLS明显低于轻度OSAS组,差异有统计学意义(P<0.05)。结论:三维应变各参数能够敏感反映OSAS患者右心功能的改变,为临床早期进行干预提供了较为详细的依据。Objective To evaluate the right ventricular systolic function in obstructive sleep apnea syndrome(OSAS)patients with normal left ventricular ejection syndrome by using three-dimensional speckle tracking imaging(3D-STI),and to explore the relationship between right ventricular strain and sleep apnea.Method Sixty cases of patients clinically diagnosed as OSAS were selected,which were divided into mild group,moderate group and severe group according to the Apnea Hypopnea index,with 20 cases in each group,and another 20 healthy cases as negative control group;Normal ultrasound and 3D-STI were used to measure the right ventricle function indexes of each group and compare the differences of parameters among the groups.Results The global longitudinal strain(GLS),circular strain(GCS)and radial strain(GRS)of OSAS patients were compared with the normal control group,and their values were significantly reduced,showing a significant difference(P<0.05);There were statistically significant differences in GLS,GCS,GRS,right ventricular Tei index and TAPSE between the severe OSAS group and the mild and moderate OSAS group(P<0.05);GLS of patients with moderate OSAS were significantly lower than those with mild OSAS,showing significant differences(P<0.05).Conclusion Three-dimensional strain parameters can be sensitive to changes in right heart function in patients with OSAS,providing more detailed evidence for early clinical intervention.

关 键 词：睡眠呼吸暂停 阻塞性 三维斑点追踪 应变 

分 类 号：R740[医药卫生—神经病学与精神病学]