子宫内膜去分化癌的分子学特征及诊治进展  

作　　者：李爱华[1] 张丽丽[1] 张师前[2] 

机构地区：[1]聊城市人民医院妇科,252000 [2]山东大学齐鲁医院妇产科

出　　处：《妇产与遗传（电子版）》2019年第3期42-45,共4页Obstetrics-Gynecology and Genetics (Electronic Edition)

摘　　要：子宫内膜去分化癌是子宫内膜癌少见但高度侵袭性的亚型,由低级别(G1/G2)子宫内膜样腺癌和未分化癌共同组成,由于其特殊的组织形态特点,在临床实践中容易漏诊或误诊,免疫组化或特殊染色有助于鉴别。子宫内膜去分化癌恶性程度高,预后差,了解去分化型子宫内膜癌的分子学特征,加强对此类疾病的认识,明确诊断、正确治疗非常重要。Dedifferentiated endometrial carcinoma is a rare but highly aggressive subtype of endometrialcarcinoma,consistingoflow-grade(G1/G2)endometrialadenocarcinoma andundifferentiated carcinoma.Due to its special histomorphological characteristics,it is easy to miss or misdiagnose in clinical practice.Immunohistochemistry or special staining is helpful for identification.Dedifferentiated endometrial carcinoma has high malignancy and poor prognosis,therefore,to understand its molecular characteristics,strengthen its understanding,make clear diagnosis and correct treatment are of great importance.

关 键 词：子宫内膜癌 子宫内膜去分化癌 诊断 鉴别 

分 类 号：R737.3[医药卫生—肿瘤]