凝血生化因素与口腔颌面部游离组织瓣移植血管危象的相关性分析  

Correlation of biochemical factors of coagulation and vascular crisis after oral and maxillofacial free tissue transplantation

作　　者：刘畅[1] 张凯[1] 李建成[1] 陈永锋[1] 刘亮[1] LIU Chang;ZHANG Kai;LI Jian-cheng;CHEN Yong-feng;LIU Liang(Department of Stomatology,the First Affiliated Hospital of Bengbu Medical College,Bengbu 233000,Anhui Province,China)

机构地区：[1]蚌埠医学院第一附属医院口腔科,安徽蚌埠233000

出　　处：《中国口腔颌面外科杂志》2020年第2期148-150,共3页China Journal of Oral and Maxillofacial Surgery

摘　　要：目的:探讨凝血生化因素对口腔游离组织瓣移植术后发生血管危象的影响。方法:对蚌埠医学院第一附属医院口腔颌面外科2012年1月1日—2018年12月31日完成游离组织瓣移植手术的226例患者的临床资料进行回顾,采用SPSS 22.0软件包对所得数据进行统计学分析。结果:统计学分析显示,低密度脂蛋白偏高(P=0.037,OR=1.435)、纤维蛋白原偏高(P=0.037,OR=1.380)是口腔颌面部游离组织瓣移植发生血管危象的危险因素。结论:术前低密度脂蛋白及纤维蛋白原偏高,可能与口腔颌面部游离组织瓣移植术后血管危象的发生有关。PURPOSE:To investigate the effects of biochemical factors of coagulation on vascular crisis after oral and maxillofacial free tissue transplantation.METHODS:Clinical data of 226 patients with oral and maxillofacial free revascularized flaps performed in our department from January 2012 to December 2018 were reviewed.Statistical analysis was conducted using SPSS 22.0 software package.RESULTS:Logistic regression analysis showed that low density lipoprotein(P=0.037,OR=1.435)and fibrinogen(P=0.037,OR=1.380)were significant factors for vascular crisis.CONCLUSIONS:Increased fibrinogen and LDL may raise the risk of vascular crisis of free flap for oral and maxillofacial reconstruction.

关 键 词：游离皮瓣移植 低密度脂蛋白 纤维蛋白原 血管危象 

分 类 号：R782[医药卫生—口腔医学]